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| DATE | OPPONENT | SCORE | IP | H | R | ER | BB | K'S | MONEY | OU | RECAP |
| 05/03/2010 | vs St. Louis | L 3-6 | 6⅔ | 10 | 4 | 4 | 1 | 4 | -$100 | U (9½) | Recap |
| 05/08/2010 | vs Atlanta | L 1-4 | 6 | 5 | 3 | 3 | 2 | 3 | -$150 | U (10) | Recap |
| 05/15/2010 | at Milwaukee | W 10-6 | 7 | 6 | 5 | 5 | 1 | 5 | $110 | O (9½) | Recap |
| 05/20/2010 | vs Chi Cubs | W 5-4 | 7 | 5 | 3 | 3 | 1 | 3 | $100 | P (9) | Recap |
| 05/26/2010 | at NY Mets | L 0-5 | 5⅓ | 6 | 5 | 5 | 4 | 2 | -$120 | U (8½) | Recap |
| 05/31/2010 | at Atlanta | L 3-9 | 6 | 8 | 6 | 4 | 1 | 2 | -$100 | O (7½) | Recap |
| 06/06/2010 | vs San Diego | L 5-6 | 5 | 11 | 5 | 5 | 0 | 3 | -$160 | O (9½) | Recap |
| 06/12/2010 | at Boston | L 2-10 | 4 | 13 | 9 | 9 | 1 | 4 | -$100 | O (10) | Recap |
| 06/18/2010 | vs Minnesota | W 9-5 | 6 | 7 | 3 | 3 | 3 | 1 | $100 | O (10) | Recap |
| 06/24/2010 | vs Cleveland | W 12-3 | 7⅔ | 6 | 3 | 3 | 0 | 8 | $100 | O (9½) | Recap |
| 06/29/2010 | at Cincinnati | W 9-6 | 7⅔ | 8 | 3 | 3 | 2 | 2 | $105 | O (9½) | Recap |
| 07/04/2010 | at Pittsburgh | L 5-8 | 6⅓ | 6 | 5 | 5 | 0 | 7 | -$135 | O (8½) | Recap |
| 07/09/2010 | vs Cincinnati | W 9-7 | 5⅓ | 12 | 6 | 5 | 2 | 7 | $100 | O (9½) | Recap |
| 07/16/2010 | at Chi Cubs | L 3-4 | 7 | 5 | 3 | 3 | 3 | 8 | -$100 | U (10) | Recap |
| 07/21/2010 | at St. Louis | L 1-5 | 7 | 7 | 5 | 3 | 1 | 3 | -$100 | U (8½) | Recap |
| 07/26/2010 | vs Colorado | W 5-4 | 6 | 6 | 2 | 2 | 3 | 2 | $100 | O (8½) | Recap |
| 07/31/2010 | at Washington | 0-0 | | 0 | 0 | 0 | 0 | 0 | NaN | | |
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