The Sabres beat Atlanta 4-1 on Wednesday, earning a victory backstopped by Ryan Miller's Ryan MillerSaves saves.
Buffalo won as a -103 underdog, while Over-Under bettors who played UNDER the total of 5.5 were rewarded at the payout window.
Cody McCormick, Thomas Vanek, Tyler Myers, and Tyler Ennis each scored for the Sabres in the victory. Ennis opened the scoring for Buffalo, finding the back of the net at 5:03 of the first period. The goal was assisted by Steve Montador and Chris Butler.
Ryan Miller turned in a 17-save effort for the Sabres.
Tobias Enstrom scored for the Thrashers, finding the net behind Ryan Miller.
Chris Mason stopped 38 of 42 shots for the Thrashers, but it wasn't enough to earn the victory.
On the power play, Buffalo went 1-for-7, while the Thrashers were 1-for-4 with the man advantage.
Buffalo outshot Atlanta 42-18 in the game.
Buffalo heads into a battle against the Senators. Atlanta, meanwhile, will have their next action against Tampa Bay.