New York was shut out 3-0 on Tuesday, stoned by Marc-Andre Fleury who stopped all 33 shots fired his way.
Pittsburgh was favored by -118 and came through for bettors backing them. The game went UNDER the consensus closing total of 5.5.
Pittsburgh got goals from Richard Park, Pascal Dupuis, and Jordan Staal in the victory. Dupuis opened the scoring at 17:06 of the first period.
Marc-Andre Fleury turned in a 33-save effort for the Penguins.
Evgeni Nabokov stopped 26 of 28 shots for the Islanders, but it wasn't enough to earn the victory.
Pittsburgh scored 0 times on 2 chances on the power play, while New York went 0-for-2 with the man advantage.
Pittsburgh lost the shots on goal battle to New York by a margin of 33-29.