Columbus's defense, led by netminder Steve Mason, shut down Colorado 2-0 at Pepsi Center on on Thursday.
Columbus won as a +195 underdog, while Over-Under bettors who played UNDER the total of 5.5 were rewarded at the payout window.
Columbus got goals from Fedor Tyutin and Nikita Nikitin in the victory. Nikitin opened the scoring at 12:53 of the first period.
Steve Mason turned in a 33-save effort for the Blue Jackets.
Colorado got a 26-stop effort from Semyon Varlamov in the loss.
Columbus scored 1 time on 2 chances on the power play, while Colorado went 0-for-2 with the man advantage.
Columbus lost the shots on goal battle to Colorado by a margin of 33-28.
Next game, Columbus takes its act on the road to face Phoenix looking for another win. For Colorado, they head home to face Pittsburgh.