| DATE | PLAYER | DESCRIPTION |
| 07/29/2010 | Jonathan Villar | Traded to Houston |
|
07/29/2010 | J.A. Happ | Traded to Houston |
|
07/29/2010 | Anthony Gose | Traded to Houston |
|
07/29/2010 | Roy Oswalt | Acquired from Houston |
|
07/28/2010 | Shane Victorino | Placed on 15-day disabled list |
|
07/28/2010 | Domonic Brown | Contract purchased from Lehigh Valley (AAA) |
|
07/25/2010 | Jamie Moyer | Placed on 15-day disabled list |
|
07/25/2010 | Vance Worley | Optioned to Lehigh Valley (AAA) |
|
07/25/2010 | J.A. Happ | Recalled from Lehigh Valley (AAA) |
|
07/22/2010 | Timo Perez | Signed to minor league contract |
|
07/21/2010 | Vance Worley | Contract purchased from Lehigh Valley (AAA) |
|
07/21/2010 | Andrew Carpenter | Optioned to Lehigh Valley (AAA) |
|
07/20/2010 | Andrew Carpenter | Recalled from Lehigh Valley (AAA) |
|
07/20/2010 | Kyle Kendrick | Optioned to Lehigh Valley (AAA) |
|
07/17/2010 | Placido Polanco | Activated from 15-day disabled list |
|
07/17/2010 | Juan Castro | Released |
|
07/15/2010 | Antonio Bastardo | Optioned to Lehigh Valley (AAA) |
|
07/15/2010 | Antonio Bastardo | Activated from 15-day disabled list |
|
07/15/2010 | Chad Durbin | Activated from 15-day disabled list |
|
07/15/2010 | Nelson Figueroa | Designated for assignment |
|
07/12/2010 | Dane Sardinha | Sent outright to Lehigh Valley (AAA) |
|
07/10/2010 | Dane Sardinha | Designated for assignment |
|
07/10/2010 | Carlos Ruiz | Activated from 15-day disabled list |
|
07/07/2010 | Mike Zagurski | Optioned to Lehigh Valley (AAA) |
|
07/07/2010 | Ryan Madson | Activated from 15-day disabled list |
|
07/06/2010 | J.A. Happ | Optioned to Lehigh Valley (AAA) |
|
07/06/2010 | J.A. Happ | Activated from 15-day disabled list |
|
07/03/2010 | Brian Bocock | Designated for assignment |
|
07/03/2010 | Cody Ransom | Contract purchased from Lehigh Valley (AAA) |