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Betting on March Madness regions

March Madness is here, the top seeds are picked and now is the time to fill out your bracket and make your NCAA hoops future bets, starting with who you think will win each region.

And it doesn't come as a huge surprise that online sportsbooks offering these odds would list the No. 1 seeds with the best region odds. Ditto when it comes to the overall college national champion, where the top seeds are the best bets. has the top seeds from each bracket as having the best odds to win the Big Dance.

The team with the best odds is North Carolina (3-1) followed by Louisville (5-1), Pittsburgh (6-1), and UCONN (7-1). Basketball bettors might want to rename the Big East as 'The Big Beast' as that conference boasts three of the top four teams with the best odds to win it all.

Other teams that have decent odds are Memphis (8-1), Oklahoma (12-1), Duke (15-1), Michigan State (15-1), and Syracuse (15-1).

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East Region Odds

In terms of East region odds, has top-seeded Pittsburgh as 3-2 odds followed by Duke (3-1), Villanova (5-1), and Texas (8-1). Even though Texas has the fourth best odds they lost to lowly Baylor in the Big 12 Tournament and they only won three of their last six games.

UCLA is at 8/1 and they are the sixth seed, but even though they lost to USC in the Pac 10 Tournament they won their previous five games.


West Region Odds

West region odds at is dominated by top-seeded UCONN at 2-1 followed by Memphis (5-2), Missouri (5-1), and Purdue (7-1). Mizzu may be a good pick, as the Tigers won the Big 10 Tournament and come into the Big Dance winning 11 of their last 13 games including their last three.

You may want to hold off betting on sixth seeded Marquette (10-1), as they lost five of their last six games.

Midwest Region Odds

Midwest region odds sees top-seeded Louisville at 3/2 followed by Michigan State (7-2), Wake Forrest (5-1) and West Virginia (6-1) and Kansas (6-1). The defending champion Kansas Jayhawks are the third seed in the Midwest, but they dropped two of their last three games including losing to a weak Baylor team in the Big 12 Tournament.

No. 10 USC (30-1) comes into the Big Dance on fire, as they won their last five games including winning the Pac 10 Tournament over Arizona State Sunday.

South Region Odds

In terms of South region odds, has top-seeded North Carolina at 2/3 followed by Oklahoma (4-1), Gonzaga (7-1) and Syracuse (8-1). Even though Louisville beat Syracuse in the Big East championship game the Orangemen won their previous seven games.

Stay away from seventh seeded Clemson (10-1), as they lost four of their last five games.

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