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Cleveland Indians vs Chicago White Sox MLB Baseball Betting Lines Preview

The Chicago White Sox will look to bolster their win total and reward those moneyline betting when the Cleveland Indians invade U.S. Cellular Field on Wednesday.

It's a pitching duel between Jose Quintana for the Chicago White Sox (5-3 on the year) and Corey Kluber for Cleveland Indians (3-5 so far).

Opening Odds & Computer Pick

Chicago was a -119 moneyline favorites earlier in the day at BetOnline, based on the starting pitcher matchup. That pairing made odds makers at 5Dimes pick an opening over under number of 7.

Prediction-scoring formulas run on this game pick a potential 4.2-3.4 result in favor of the White Sox. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Cleveland Indians vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox sport a record of 27-20 heading into this matchup, while the Cleveland Indians sit at 24-20 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Cleveland injuries news.

The Chicago White Sox sit at No. 6 in the current MLB power poll here at Odds Shark, while the Cleveland Indians sit at No. 7 on the same chart.

Statistical Matchup

Scoring stats point to some edges in this matchup. The game features the Chicago White Sox No. 17-ranked scoring average of 4.11 runs per game, against a Cleveland Indians offense rated No. 6 and scoring 4.77 runs per game. The White Sox have averaged 8.38 hits per game to date this season, less than the Indians hitters have managed (8.66 per nine innings).

Chicago owns the No. 4 defense, allowing 4.11 men per game to cross the plate. That contrasts with Cleveland's No. 11-rated defense.

Recent Outings Betting Recap

Cleveland got the job done in their last match in a 6-2 victory over Chicago on Tuesday at U.S. Cellular Field behind starter J Tomlin.

Betting Trends
  • Cleveland is 7-3 SU in its last 10 games
  • Cleveland is 4-2 SU in its last 6 games when playing Chi White Sox
  • The total has gone OVER in 7 of Cleveland's last 10 games when playing Chi White Sox
  • Cleveland is 8-3 SU in its last 11 games when playing on the road against Chi White Sox
  • Chi White Sox is 3-8 SU in its last 11 games
  • The total has gone UNDER in 6 of Chi White Sox's last 8 games
  • Chi White Sox is 2-4 SU in its last 6 games at home
  • The total has gone UNDER in 6 of Chi White Sox's last 8 games at home

Next Betting Matchups

Cleveland home to Baltimore, Friday, May 27th
Chicago at Kansas City, Thursday, May 26th

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