Cleveland Indians vs Chicago White Sox in MLB Betting Odds

Those betting on MLB baseball odds will look to pick a Sportsbook at U.S. Cellular Field on Wednesday as the host Chicago White Sox battle the Cleveland Indians in baseball betting odds action.

Carlos Rodon gets the call for the Chicago White Sox and he will try to build on a 7-8 mark. In the other dugout, Josh Tomlin brings a 11-8 ledger to the game for the Cleveland Indians as he tries to quiet the White Sox bats.

Sportsbook Odds & Computer Pick

On the MLB moneyline for this betting odds matchup, Chicago sat as -105 earlier in the day at Sportsbook. The over/under total was set at 8.5, according to Sportsbook.

Odds Shark computer score prediction models pick a possible 5.6-3.7 win for the White Sox on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Cleveland Indians vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

Chicago (70-74) will face the 83-61 Indians in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Cleveland injuries news.

The Odds Shark MLB Power Rankings have the Chicago White Sox at No. 14 and the Cleveland Indians at No. 15 heading into this contest.

Statistical Matchup

At the plate, Chicago owns the No. 13 ranking for hits at 8.81 per game. By contrast, the Cleveland Indians are rated No. 6 in the same category at 9.08 per game.

Comparing defensive stats, Cleveland owns the No. 7-rated road mark, allowing 4.11 runs per game on the highway. Chicago, on the other hand, rates No. 21 in scoring at home.