Colorado Rockies vs San Diego Padres MLB Baseball Betting Lines Preview

The San Diego Padres battle the visiting Colorado Rockies on Wednesday in MLB betting odds action at PETCO Park.

The San Diego Padres will rely on Jered Weaver to turn in a quality outing on the mound in this one, while Antonio Senzatela will be his counterpart for the Colorado Rockies. Jered Weaver is 0-2 this season, and Antonio Senzatela is 3-1.

Sportsbook Odds & Computer Pick

Baseball betting odds makers, including Sportsbook, opened the San Diego Padres as 100 moneyline underdogs in this matchup. Over under total bettors saw the number open at 8 at shops such as Sportsbook.

Odds Shark prediction models pick the Padres to win this game 5.4-3.1. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Colorado Rockies vs San Diego Padres Matchup

Team Betting Records & Power Rankings

San Diego (12-16) will face the 16-11 Rockies in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Diego vs Colorado injuries news.

The San Diego Padres vs Colorado Rockies odds would favor the Rockies if the betting lines were set according to our power ranks. San Diego is rated No. 26 in the current Odds Shark poll, while Colorado is at No. 20.

Statistical Matchup

The game also pits San Diego Padres No. 24-rated offense, averaging 3.86 runs per game, against a Colorado Rockies defense that ranks No. 25 at 4.85 in runs allowed per game. The San Diego Padres have averaged 7.32 hits per game so far, less than Colorado Rockies batters have averaged on the year (8.22 hits per game).

Pitching and defensive stats are important baseball handicapping betting factors and San Diego has the No. 22-ranked defense. In the other dugout, the Rockies own the No. 25 mark in runs allowed.