Miguel Gonzalez White Sox at Home vs Houston Astros in MLB Betting Odds Clash

The Houston Astros will look to pick up a road win when they take on the White Sox in Chicago at Guaranteed Rate Field on Wednesday in MLB baseball betting odds action.

It's a pitching duel between Miguel Gonzalez for the Chicago White Sox (5-10 on the year) and Collin McHugh for Houston Astros (0-0 so far).

Sportsbook Odds & Computer Pick

The Chicago White Sox were listed as 194 moneyline underdogs earlier in the day at Sportsbook, while odds makers set the Sportsbook total line around 10 earlier at Sportsbook.

Odds Shark computer prediction formulas pick a 5.8-4.4 win for the Astros on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Houston Astros vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox bring a 42-68 record to the battle against the 71-41 Astros. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Houston injuries news.

The Odds Shark MLB Power Rankings have the Chicago White Sox at No. 30 and the Houston Astros at No. 14 heading into this contest.

Statistical Matchup

At the plate, Chicago owns the No. 13 ranking for hits at 8.7 per game. By contrast, the Houston Astros are rated No. 1 in the same category at 10.21 per game.

Comparing defensive stats, Houston owns the No. 15-rated road mark, allowing 4.65 runs per game on the highway. Chicago, on the other hand, rates No. 19 in scoring at home.