Houston Astros vs Oakland Athletics in MLB Betting Odds

The Houston Astros will look to pick up a road win when they take on the Athletics in Oakland at O.co Coliseum on Saturday in MLB baseball betting odds action.

Collin McHugh gets the ball in front of a hostile crowd for the Houston Astros on Saturday; he's 13-5 on the season. The Oakland Athletics, meanwhile, will counter with Jesse Chavez, who will be looking to improve on his 5-11 mark.

Sportsbook Odds & Computer Pick

The Oakland Athletics were listed as 107 moneyline underdogs earlier in the day at Sportsbook, while odds makers set the Sportsbook total line around 7.5 earlier at Sportsbook.

Prediction-scoring formulas run on this game pick a potential 4.5-3.3 result in favor of the Astros. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Houston Astros vs Oakland Athletics Matchup

Team Betting Records & Power Rankings

The Oakland Athletics sport a record of 49-62 heading into this matchup, while the Houston Astros sit at 61-49 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Oakland vs Houston injuries news.

The Oakland Athletics vs Houston Astros odds would favor the Astros if the betting lines were set according to our power ranks. Oakland is rated No. 22 in the current Odds Shark poll, while Houston is at No. 4.

Statistical Matchup

The game also pits Oakland Athletics No. 17-rated offense, averaging 4.11 runs per game, against a Houston Astros defense that ranks No. 5 at 3.73 in runs allowed per game. The Oakland Athletics have averaged 8.57 hits per game so far, more than Houston Astros batters have averaged on the year (8.17 hits per game).

Defensively, Houston features the No. 10-rated defense on the road, allowing 4.09 runs per game. Oakland, meanwhile, comes in at No. 15 at home, scoring 4.12 runs per game.