Minnesota Twins at Chicago White Sox Betting Odds and Pick

The Chicago White Sox look to emerge victorious in MLB odds action as the Minnesota Twins arrive at Guaranteed Rate Field on Wednesday.

It's a pitching duel between Derek Holland for the Chicago White Sox (3-2 on the year) and Phil Hughes for Minnesota Twins (4-1 so far).

Sportsbook Odds & Computer Pick

Betting fans looking to pick the visiting Minnesota Twins before the first pitch in this match found them as 111 moneyline underdogs earlier today at Sportsbook. They saw the over/under total of 8.5 earlier at Sportsbook.

Odds Shark computer score prediction models pick a possible 5.5-4.0 win for the White Sox on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Minnesota Twins vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox sport a record of 15-16 heading into this matchup, while the Minnesota Twins sit at 16-14 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Minnesota injuries news.

The Odds Shark MLB Power Rankings have the Chicago White Sox at No. 12 and the Minnesota Twins at No. 24 heading into this contest.

Statistical Matchup

When it comes to getting on base, the visiting Minnesota Twins rank No. 18 at 8.23 hits per game. That compares with the Chicago White Sox No. 23 ranking in that category.

Defensively, Minnesota features the No. 7-rated defense on the road, allowing 4 runs per game. Chicago, meanwhile, comes in at No. 13 at home, scoring 4.75 runs per game.