Moneyline Favors Chicago White Sox in MLB Battle with Oakland Athletics

The Oakland Athletics will look to pick up a road win when they take on the White Sox in Chicago at Guaranteed Rate Field on Friday in MLB baseball betting odds action.

Chicago sends Mike Pelfrey out against Jharel Cotton for the Oakland Athletics in this game. Pelfrey is 3-5 with a 3.56 ERA on the season, while Cotton is 4-7 on the year and has a 5.40 ERA.

Sportsbook Odds & Computer Pick

Baseball betting odds makers, including Sportsbook, opened the Chicago White Sox as -109 moneyline favorites in this matchup. Over under total bettors saw the number open at 10 at shops such as Sportsbook.

Handicapping models based on recent betting stats and prediction formulas pick a 5.6-4.0 win for the White Sox. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Oakland Athletics vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox sport a record of 32-39 heading into this matchup, while the Oakland Athletics sit at 31-42 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Oakland injuries news.

This game puts the Chicago White Sox, most recently No. 20 in Odds Shark MLB Power Rankings, up against the Oakland Athletics, who rate a No. 27 in the latest survey.

Statistical Matchup

The game also pits Chicago White Sox No. 18-rated offense, averaging 4.68 runs per game, against a Oakland Athletics defense that ranks No. 29 at 5.45 in runs allowed per game. The Chicago White Sox have averaged 9.11 hits per game so far, more than Oakland Athletics batters have averaged on the year (8.07 hits per game).

Pitching and defensive stats are important baseball handicapping betting factors and Chicago has the No. 14-ranked defense. In the other dugout, the Athletics own the No. 29 mark in runs allowed.