Pittsburgh Pirates Favored by -165 Against San Diego Padres on Wednesday

The San Diego Padres pay a visit to Pittsburgh on Wednesday, hoping to shut down the Pirates bats in baseball betting action at PNC Park.

For the Pittsburgh Pirates, Ryan Vogelsong gets the ball, charged with keeping the San Diego Padres hitters off the base paths. He'll face Edwin Jackson, 2-2 on the year.

Sportsbook Odds & Computer Pick

Those going with the Pittsburgh Pirates in this one found them listed on the odds board as moneyline favorites of -165 at Sportsbook for Wednesday's contest. The betting total was hovering near 9 at Sportsbook.

Odds Shark computer prediction formulas pick a 4.5-4.1 win for the Padres on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs Pittsburgh Pirates Matchup

Team Betting Records & Power Rankings

The Pittsburgh Pirates sport a record of 56-54 heading into this matchup, while the San Diego Padres sit at 48-64 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Pittsburgh vs San Diego injuries news.

The Pittsburgh Pirates vs San Diego Padres odds would favor the Padres if the betting lines were set according to our power ranks. Pittsburgh is rated No. 26 in the current Odds Shark poll, while San Diego is at No. 15.

Statistical Matchup

When it comes to getting on base, the visiting San Diego Padres rank No. 25 at 8.23 hits per game. That compares with the Pittsburgh Pirates No. 14 ranking in that category.

Pitching and defensive stats are important baseball handicapping betting factors and Pittsburgh has the No. 18-ranked defense. In the other dugout, the Padres own the No. 26 mark in runs allowed.