MLB Odds with Pick - San Francisco Giants vs Colorado Rockies

The visiting San Francisco Giants hope for a solid performance on Wednesday as they look to pick up a win at Coors Field against the Colorado Rockies.

Colorado sends Jordan Lyles out against Jake Peavy for the San Francisco Giants in this game. Lyles is 0-1 with a 13.51 ERA on the season, while Peavy is 0-0 on the year and has a 7.20 ERA.

Sportsbook Odds & Computer Pick

Colorado was a 120 moneyline underdogs earlier in the day at Sportsbook, based on the starting pitcher matchup. That pairing made odds makers at Sportsbook pick an Sportsbook over under number of 11.

Handicapping models based on recent betting stats and prediction formulas pick a 6.9-3.6 win for the Giants. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs Colorado Rockies Matchup

Team Betting Records & Power Rankings

The Colorado Rockies sport a record of 3-4 heading into this matchup, while the San Francisco Giants sit at 6-2 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Colorado vs San Francisco injuries news.

The Odds Shark MLB Power Rankings have the Colorado Rockies at No. 29 and the San Francisco Giants at No. 12 heading into this contest.

Statistical Matchup

On offense, it's a battle between the Colorado Rockies and its No. 9-rated batting order, averaging 5.29 runs per nine innings, against the No. 4 line up of the San Francisco Giants at 6.25 runs per outing.

Comparing defensive stats, San Francisco owns the No. 8-rated road mark, allowing 2.5 runs per game on the highway. Colorado, on the other hand, rates No. 14 in scoring at home.