San Francisco Giants visit San Diego Padres in MLB Betting Odds Clash

The San Diego Padres will look to improve on a 64-89 record when they take on the San Francisco Giants, a key part of the MLB betting odds line up on Friday.

The San Diego Padres will turn to Edwin Jackson and his 4-6 record as they look for a win in this one, while the San Francisco Giants send Albert Suarez (3-4) to the hill.

Sportsbook Odds & Computer Pick

Baseball betting odds makers, including Sportsbook, opened the San Diego Padres as 135 moneyline underdogs in this matchup. Over under total bettors saw the number open at 8.5 at shops such as Sportsbook.

Handicapping models based on recent betting stats and prediction formulas pick a 3.4-2.4 win for the Giants. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs San Diego Padres Matchup

Team Betting Records & Power Rankings

The San Diego Padres sport a record of 64-89 heading into this matchup, while the San Francisco Giants sit at 81-72 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and San Diego vs San Francisco injuries news.

The MLB Power Rankings show a disparity between these teams, with the San Diego Padres rated this week at No. 19 and the San Francisco Giants sitting at No. 15.

Statistical Matchup

Offensively, the game matches up San Diego Padres No. 22 ranked offense (4.2 runs per game) against a San Francisco Giants defense and pitching staff that sits at No. 5 at 3.94 runs allowed per game. The San Diego Padres have been averaging 7.82 hits per game, less than the San Francisco Giants have managed so far this season (8.78 hits on average).

San Francisco brings the No. 5-rated defense to this matchup, facing the Padres's No. 24-ranked defense.