College hoops betting interest focuses on the Louisville vs Notre Dame battle Friday at Madison Square Garden as the Cardinals look to defend home court and cover the NCAA basketball point spread.

This game is part of the Big East Tournament which will decide the conference champion and help decide March Madness seedings. This game is being played at a neutral-site court (Madison Square Garden).

The Cardinals are 27-5 so far on the season, and 18-13-1 ATS vs. the number. The Fighting Irish, meanwhile, are 25-8 and 16-14 ATS. OVER/UNDER bettors have seen Louisville go 13-16 and the Fighting Irish go 15-12 on the totals.



View Notre Dame vs Louisville Odds and Stats.

Power Rankings / Prediction:
The Odds Shark Power Rankings have the Cardinals at No. 1 and the Fighting Irish at No. 46 heading into this contest. Handicapping models at Odds Shark project a 82-74 result in favor of the Cardinals.



How They Match Up:
Scoring and defensive stats point to some edges in this matchup. The game features Louisville's No. 46-ranked scoring average of 73.6 PPG, against a Fighting Irish defense rated No. 85 and allowing 62.9 PPG. The Cardinals FG% has averaged 44.6% to date this season, less than the Fighting Irish shooters have managed so far (46.6% per game).

Defensively, Notre Dame features the nation's No. 98-rated defense on the road, allowing 66.3 points per game. Louisville, meanwhile, comes in at No. 70 nationally in scoring at home.

Last time out for Notre Dame, they were a 73-65 Sportsbook as they battled Marquette on the road. They covered in the match as a 3-point underdog. The Fighting Irish got 18 points from Pat Connaughton as Notre Dame ran past Marquette 73-65 on Thursday at Madison Square Garden.

Louisville was a 74-55 Sportsbook in their most recent outing at home against Villanova. They covered the 10.5-point spread as favorites. The Cardinals got a terrific 28-point effort from Russ Smith as Louisville defeated Villanova 74-55 on Thursday at Madison Square Garden.