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Biggest Potential March Madness Upsets

The NCAA Tournament provides lesser-known schools with the chance to play Cinderella on college basketball’s biggest stage. Over the past two years, five No. 12 seeds and three No. 11 seeds have defied the odds, scoring some of the biggest upsets in March Madness history. The stage is set once again for the underdog to prevail on the hardwood at this year's NCAA Tournament.

No. 12 Harvard Crimson (+3 at Bovada) over No. 5 Cincinnati Bearcats

Harvard was the first team to secure a March Madness berth this year. They enter the tourney riding an eight-game winning streak SU (6-2 ATS), and will be looking to play spoiler for the second straight year after knocking off New Mexico as a No. 14 seed a year ago. Cincy enters the tourney 3-3 SU in their last six, 1-4 ATS in their last five.

No. 12 Stephen F. Austin Lumberjacks (+6.5 at Bovada) over No. 5 Virginia Commonwealth Rams

The 26-8 Rams (18-14 ATS) have been ranked in the middle of the pack all season. They were on a 6-0 run (SU & ATS) before being upset 65-61 by unranked St. Joseph's in the A-10 title game. VCU will be playing their fourth game in a week when they face SFA, who have not lost since November, dominated in their 68-49 win over Sam Houston in the Southland Tournament title game, and own the 10th-best road defense in the nation (62.13 PPG).

No. 12 North Dakota State Bison (+3.5 at Bovada) over No. 5 Oklahoma Sooners

Oklahoma was strong down the stretch, going 5-1 SU (6-0 ATS). But the young Sooners were asleep at the switch in their 78-73 loss to Baylor in the Big 12 Tournament quarterfinals. The Bison, winners of their last nine SU, have strength inside and out, and are stacked with seniors who are looking to end their collegiate careers on a winning note.

No. 11 Nebraska Cornhuskers (+3.5 at Bovada) over No. 6 Baylor Bears

Baylor clawed back into the national rankings with their gutsy win over Oklahoma, but were outclassed by Iowa State in the Big 12 Tournament final. The Bears were 6-0 SU prior to their loss to Iowa State, but are a mediocre 9-8-1 ATS as favorites this season. Baylor is 3-1 SU in their last four versus Nebraska, but only 1-3 ATS. The Cornhuskers may be due for a win over a familiar foe.

No. 11 Dayton Flyers (+6 at Bovada) over No. 6 Ohio State Buckeyes

The Buckeyes have lost three of their last six SU (0-6 ATS), and came out flat in a 72-69 loss to Michigan in the Big Ten semifinals. Ohio State will need to find their early season form, during which they won 15 straight SU (8-6 ATS) to hold off a Dayton team that won as a No. 11 seed in their last March Madness appearance in 2009. The Flyers are 10-2 SU (8-4 ATS) in their last 12 and 2-1 SU against nationally-ranked teams this season.

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2013 BIGGEST POTENTIAL MARCH MADNESS UPSETS

No. 9 Villanova (+4.0) over No. 8 North Carolina

UNC finished the season on an 8-2 SU run, but has an 0-5 SU record in its last five games against ranked opponents. Villanova isn’t ranked, but it is a quality team featuring two players in Ryan Arcidiacono and Mouphtaou Yarou that are capable of getting hot and leading the team to an upset here in the Round of 64 and maybe even against No. 1 Kansas.

No. 12 Oregon (+3.0) over No. 5 Oklahoma State

Playing relentless defense and getting balanced scoring across the board, Oregon is exactly the type of team you hate to draw in the first round. After ending the regular season in a slump, Oregon rallied to win the Pac-12 (3-0 SU, 2-1 ATS) and looks to be geared up for a nice run in the tournament.

No. 11 Belmont (+4.5) over No. 6 Arizona

After starting the season off on a 14-0 run, Arizona turned out to be pretty pedestrian down the stretch with a 5-5 SU and 4-6 ATS record over its last 10 games. Belmont enters the game with six straight wins (3-3 ATS), and as a great 3-point shooting team going up against Arizona’s shaky offense, should be able to put up enough offense to give Arizona a run.

No. 12 California (+3.0) over No. 5 UNLV

A mix-up by the NCAA selection committee landed Cal this virtual home game played in San Jose. Cal finished the season on a low note with two losses but was 7-0 SU and 5-1-1 ATS in its previous seven games including wins over Arizona, UCLA, and Oregon. A favorable crowd could get Cal back on track and make them a serious threat to UNLV.

No. 15 Iona (+14.0) over No. 2 Ohio State

Looking for a home run upset? This could be it. Obviously a team like Iona would have to catch Ohio State sleeping for an outright upset. However, if Ohio State comes in over-confident after winning the Big Ten Tournament and gets caught looking ahead, Iona has the offense (second in the nation averaging 80.7 PPG) to pull off a stunner.