The NCAAF betting menu features a clash between Louisville and Syracuse on Saturday, with the host Cardinals trying to win both for fans supporting them and bettors backing them.

The Orange will try to spoil to the party on Saturday; they are 3-4 ATS against the number this season, while the Cardinals are 4-3 ATS. Syracuse is 5-2 on the totals; Louisville is 0-6-1.



View Syracuse vs Louisville Odds and Stats.

Betting Line: The home team opened as 3-point favorites in this NCAA football battle. No over under line was available early in the week, but was set to posted shortly.

Power Rankings / Prediction: This game matches up the No. 46 (Cardinals) and the No. 71 (Orange) teams in the league, according to our current NCAAF Power Rankings at OddsShark. A 26-22 result in favor of the Orange is predicted by handicapping models.



How They Match Up:
Offensively, the game matches up Louisville's No. 114-ranked offense (16.3 PPG) against a Orange defense that ranks No. 63 at 26.7 PPG. The Cardinals passing attack has averaged 207.4 yards per game, less than the Orange give up through the air (299.4 YPG on average).

Defensively, the Orange feature the league's No. 45-rated road run defense, allowing 145.5 yards per game. Louisville, meanwhile, ranks No. 100 in rushing offense at home.

Syracuse was a 49-23 Sportsbook in their most recent outing at home against West Virginia. They covered the 14.5–point spread as underdogs, while the total score (72) made Sportsbooks of OVER bettors.

Louisville was a 16-14 Sportsbook in their most recent outing at home against Rutgers. They covered the 1–point spread as favorites, while the total score (30) made Sportsbooks of UNDER bettors.


Syracuse Orange Trends:
When playing in October are 6-4
When playing on turf are 6-4
After outgaining opponent are 3-7
When playing within the conference are 5-5

Louisville Cardinals Trends:
When playing in October are 5-5
When playing on turf are 5-5
After outgaining opponent are 3-7
When playing within the conference are 4-6

A few Orange at Cardinals trends to consider:
Syracuse is 5-1 SU in its last 6 games on the road
The total has gone OVER in 4 of Syracuse's last 5 games
Syracuse is 6-2 SU in its last 8 games
The total has gone UNDER in 5 of Syracuse's last 7 games when playing Louisville
The total has gone UNDER in 5 of Louisville's last 5 games at home
The total has gone UNDER in 6 of Louisville's last 7 games
Louisville is 5-2 SU in its last 7 games when playing Syracuse
The total has gone UNDER in 5 of Louisville's last 7 games when playing Syracuse


Next up:
Syracuse at Connecticut, Saturday, November 5
Louisville at West Virginia, Saturday, November 5