Louisville Favored by -21 Against Wake Forest on Saturday - Week 5 College Football Betting Odds and Pick

Wake Forest Demon Deacons

vs

Louisville Cardinals
Saturday, September 27, 2014 3:30 PM ET
Papa John's Cardinal Stadium

Wake Forest will open play in the ACC this Saturday with a trip to Louisville to face the conference's newest member. The Demon Deacons are an even 2-2 SU and ATS through their first four games and the total has stayed UNDER in three of the four games.

Louisville has already played two games against teams in its new conference with a 31-13 win over Miami as a 6-point home favorite and a 23-21 loss to Virginia as a 4-point favorite on the road. The total has stayed UNDER in three of the Cardinals' first four games overall.

Wake Forest Demon Deacons vs Louisville Cardinals Sportsbook Odds and Betting Line

Odds makers at Sportsbook opened the Louisville Cardinals as -21-point favorites in the matchup, while the betting total had not been set at press time (check Sportsbook for the latest on the over under).

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Computer Prediction: Wake Forest Demon Deacons vs Louisville Cardinals Pick

Odds Shark computer score prediction models pick a possible 33-21 win for the Cardinals on Saturday. View the computer score prediction and who will win the pick on the moneyline for all upcoming NCAAF matchups here.

Wake Forest Demon Deacons vs Louisville Cardinals Odds and Stats.

Team Betting Records & Power Rankings

Louisville will face the 1-2 Wake Forest Demon Deacons, who own a 1-2 ATS mark on the season. In totals betting, the Louisville Cardinals are 1-3 so far this season while the Demon Deacons are 1-2. Stay Informed: follow us on Twitter for odds specials, betting line moves and Louisville vs Wake Forest injuries news.

The OddsShark Power Rankings have the Louisville Cardinals at No. 17 and the Wake Forest Demon Deacons at No. 85 heading into this contest.

How Wake Forest Demon Deacons vs Louisville Cardinals Stats Matchup

Offensively, the game matches up the Louisville Cardinals No. 37-ranked offense (38 PPG) against a Wake Forest Demon Deacons defense that ranks No. 37 at 20.25 PPG. The Louisville Cardinals passing attack has averaged 252.75 yards per game, more than the Wake Forest Demon Deacons give up through the air (148 YPG on average).

Defensively, the Wake Forest Demon Deacons feature the league's No. 29-rated road run defense, allowing 111.5 yards per game. Louisville, meanwhile, ranks No. 51 in rushing offense at home.

Recent Outings Betting Recap

Last time out for Wake Forest, they were a 24-21 Sportsbook as they battled Black Knights at home. Wake Forest covered in the match as a +2.5-point underdog, while 45 combined points moved the game UNDER for totals bettors. The Demon Deacons grabbed a Week 4 victory over the Black Knights in their last game, winning 24-21 at BB&T Field.

Last time out for Louisville, they were a 34-3 Sportsbook as they battled Golden Panthers on the road. Louisville covered in the match as a -25.5-point favorite, while 37 combined points moved the game UNDER for totals bettors. Last time out for the the Golden Panthers, they were scorched by James Quick for 174 receiving yards against the Cardinals in a 34-3 loss at FIU Stadium.

Wake Forest Demon Deacons vs Louisville Cardinals Betting Odds Trends

Wake Forest is 2-7 SU in its last 9 games
The total has gone UNDER in 18 of Wake Forest's last 23 games
Wake Forest is 0-5 SU in its last 5 games on the road
The total has gone UNDER in 9 of Wake Forest's last 12 games on the road
Louisville is 5-1 ATS in its last 6 games
Louisville is 9-1 SU in its last 10 games
The total has gone UNDER in 4 of Louisville's last 5 games
Louisville is 5-0 SU in its last 5 games at home

Next Betting Matchups

Wake Forest at Florida State, Saturday, October 4th
Louisville at Syracuse, Friday, October 3rd

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