The San Francisco 49ers are 11-3 SU and 9-5 ATS over their last 14 games against the St. Louis Rams and will be looking for another win over their division rival when they host them at Candlestick Park Sunday. The 49ers are 16-4 SU and 14-5-1 ATS in their last 20 games at home.

On the opposite side of the spectrum, St. Louis is just 1-12 SU and 3-10 ATS over its last 13 road games. The total has gone UNDER on eight of St. Louis's last 10 road games and in six of San Francisco's last nine home games.



View St Louis vs San Francisco Odds and Stats.

Betting Line:
The 49ers were listed as 11-point favorites at Sportsbook and other online sportsbooks, with the total listed at one point at 38.

Power Rankings / Prediction:
The OddsShark Power Rankings have the 49ers at No. 2 and the Rams at No. 25 heading into this contest. Handicapping models project a 30-13 result in favor of the 49ers.



How They Match Up:
Offensively, the game matches up San Francisco's No. 14-ranked offense (23.6 PPG) against a Rams defense that ranks No. 20 at 23.2 PPG. The 49ers passing attack has averaged 200.4 yards per game, less than the Rams give up through the air (237.5 YPG on average).

Defensively, the Rams feature the league's No. 4-rated road run defense, allowing 74 yards per game. San Francisco, meanwhile, ranks No. 1 in rushing offense at home.

St. Louis lost its last outing, a 45-7 result against the Patriots on October 28. The Rams failed to cover in that game as a 7-point underdog, while the 52 combined points took the game OVER the total.

San Francisco won its last outing, a 24-3 result against the Cardinals on October 29. The 49ers covered in that game as a 7-point favorite, while the 27 combined points took the game UNDER the total. Alex Smith dusted the Cardinals secondary for 3 TDs last time out as the 49ers defeated Arizona 24-3 at University of Phoenix Stadium.


St. Louis Rams Trends:
When playing in November are 2-8
When playing on grass are 3-7
After being outgained are 3-7
When playing within the division are 3-7

San Francisco 49ers Trends:
When playing in November are 7-3
When playing on grass are 7-3
After outgaining opponent are 6-4
When playing within the division are 8-2

A few Rams at 49ers trends to consider:
The total has gone UNDER in 8 of St. Louis's last 10 games on the road
The total has gone UNDER in 4 of St. Louis's last 6 games when playing on the road against San Francisco
The total has gone UNDER in 8 of St. Louis's last 12 games when playing San Francisco
The total has gone UNDER in 4 of St. Louis's last 6 games
San Francisco is 7-1 SU in its last 8 games when playing St. Louis
San Francisco is 6-1 SU in its last 7 games when playing at home against St. Louis
The total has gone UNDER in 5 of San Francisco's last 6 games
San Francisco is 10-2 SU in its last 12 games at home


Next up:
St. Louis home to NY Jets, Sunday, November 18
San Francisco home to Chicago, Monday, November 19