Eagles battle 49ers in Week 4 odds

The Eagles and 49ers have played seven times since 2002 and San Francisco bettors only came out smiling once.

But with the QB situation flighty in Philly, is this the week the 2-1 49ers can win on the road? If history repeats itself, the Eagles will have no problem scoring, as they have averaged 35 PPG in those seven games against SF.

Michael Vick has stated he will '100%' be the starter, which gives bettors some comfort. But the way he has been knocked around in three games is uncomfortable at best and online sportsbook Bovada has put on odds on whether he will be removed from the game with an injury in Week 4 and the 'no' is a surprise -250 line.

View San Francisco vs Philadelphia Odds and Stats.

Power Rankings / Prediction:
The Eagles sit at No. 14 in the current NFL Power Rankings here at OddsShark, while the 49ers are at No. 16 on that chart. Math models have concluded that the 49ers will win this game 29-23.

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How They Match Up:
Offensively, the game matches up Philadelphia's No. 10-ranked offense (26 PPG) against a 49ers defense that ranks No. 4 at 17.3 PPG. The Eagles passing attack has averaged 226.7 yards per game, less than the 49ers give up through the air (243.7 YPG on average).

In comparing defenses, the 49ers own the league's No. 6-rated front 7 in terms of stopping the run, allowing 79 yards per game when on the road. Philadelphia, on the other hand, rates No. 2 this week in generating rushing yards at home.

San Francisco won its last outing, a 13-8 result against the Bengals on September 25. The 49ers covered in that game as a 1-point underdog, while the 21 combined points took the game UNDER the total. Last time out, Cincinnati could not slow down Vernon Davis, who managed 114 receiving yards in the 49ers 13-8 victory over the Bengals Sunday.

Philadelphia lost its last outing, a 29-16 result against the Giants on September 25. The Eagles failed to cover in that game as a 7.5-point favorite, while the 45 combined points took the game UNDER the total. LeSean McCoy ran through the New York defense for 128 yards in Philadelphia's last game, but the Eagles still lost a 29-16 decision at Lincoln Financial Field.

San Francisco 49ers Trends:
When playing in October are 3-7
When playing on grass are 6-4
After being outgained are 6-4
When playing outside the division are 3-7

Philadelphia Eagles Trends:
When playing in October are 6-4
When playing on grass are 4-6
After outgaining opponent are 5-5
When playing outside the division are 5-5

A few 49ers at Eagles trends to consider:
The total has gone OVER in 6 of San Francisco's last 7 games when playing Philadelphia
The total has gone OVER in 4 of San Francisco's last 5 games
San Francisco is 5-2 SU in its last 7 games when playing on the road against Philadelphia
San Francisco is 4-8-1 ATS in its last 13 games on the road
Philadelphia is 5-0 SU in its last 5 games when playing San Francisco
The total has gone OVER in 6 of Philadelphia's last 7 games when playing San Francisco
The total has gone UNDER in 5 of Philadelphia's last 6 games at home
The total has gone UNDER in 4 of Philadelphia's last 6 games

Next up:
San Francisco home to Tampa Bay, Sunday, October 9
Philadelphia at Buffalo, Sunday, October 9

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