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NFL Betting: Week 5 Opening Lines

The Houston Texans will be gunning for their fifth straight ATS victory of the season on Monday night as a big road favorite to highlight the NFL's Week 5 opening lines at the sportsbooks.

Houston is 4-0 both ATS and SU atop the league standings this season, and they opened as favorites of +9 at 5Dimes against the New York Jets for their Monday Night Football matchup.

The Jets are one of several teams to open as home underdogs for Week 5, with that list also including the Colts +7.5 vs. the Packers, the Jaguars +5.5 vs. the Bears, the Chiefs +4.5 vs. the Ravens, and the Redskins +3 vs. the Falcons.

As well, the Rams opened at +1 at home against the Cardinals for Thursday Night Football this week, with Arizona 4-1 both SU and ATS over their past five games against St. Louis. The OVER/UNDER went 1-4 in those five contests.

The biggest favorite on the opening lines at 5Dimes for Week 5 are the New York Giants at -11 at home against the Browns - who are 0-4 SU but 2-1-1 ATS on the season.

Week 5 Opening NFL Betting Lines (from 5Dimes)

Thu - Arizona at St. Louis (+1) (8:20pm ET)

Sun - Miami at Cincinnati (-4.5) (1:00pm ET)

Sun - Green Bay at Indianapolis (+7.5) (1:00pm ET)

Sun - Baltimore at Kansas City (+4.5) (1:00pm ET)

Sun - Tennessee at Minnesota (-5) (1:00pm ET)

Sun - Atlanta at Washington (+3) (1:00pm ET)

Sun - Cleveland at NY Giants (-11) (1:00pm ET)

Sun - Philadelphia at Pittsburgh (-3.5) (1:00pm ET)

Sun - Seattle at Carolina (-3) (4:05pm ET)

Sun - Chicago at Jacksonville (+5.5) (4:05pm ET)

Sun - Denver at New England (-7.5) (4:25pm ET)

Sun - Buffalo at San Francisco (-10) (4:25pm ET)

Sun - San Diego at New Orleans (-3) (8:20pm ET)

Mon - Houston at NY Jets (+9) (8:30pm ET)

Week 5 NFL Betting Trends and Notes

Arizona at St. Louis - Matchup Report

Arizona is 5-0 SU in its last 5 games

The total has gone UNDER in 7 of St. Louis's last 8 games when playing Arizona

Philadelphia at Pittsburgh - Matchup Report

Philadelphia is 7-1 SU in its last 8 games

Pittsburgh is 11-1 SU in its last 12 games at home

Miami at Cincinnati - Matchup Report

Miami is 6-1 SU in its last 7 games when playing on the road against Cincinnati

The total has gone OVER in 7 of Cincinnati's last 8 games at home

Atlanta at Washington - Matchup Report

Atlanta is 5-1 SU in its last 6 games

The total has gone OVER in 5 of Washington's last 5 games at home

Green Bay at Indianapolis - Matchup Report

Green Bay is 21-4 SU in its last 25 games

The total has gone UNDER in 6 of Indianapolis's last 7 games

Baltimore at Kansas City - Matchup Report

The total has gone UNDER in 5 of Baltimore's last 6 games when playing on the road against Kansas City

The total has gone UNDER in 5 of Kansas City's last 6 games when playing at home against Baltimore

Cleveland at NY Giants - Matchup Report

The total has gone UNDER in 5 of Cleveland's last 6 games

The total has gone UNDER in 5 of the NY Giants last 6 games

Seattle at Carolina - Matchup Report

The total has gone UNDER in 5 of Seattle's last 6 games

The total has gone OVER in 8 of Carolina's last 11 games

Chicago at Jacksonville - Matchup Report

Chicago is 4-1 SU in its last 5 games

The total has gone UNDER in 4 of Jacksonville's last 5 games

Buffalo at San Francisco - Matchup Report

The total has gone OVER in 6 of Buffalo's last 7 games

San Francisco is 8-1 SU in its last 9 games at home

Denver at New England - Matchup Report

Denver is 17-6 SU in its last 23 games when playing New England

New England is 17-4 SU in its last 21 games at home

Tennessee at Minnesota - Matchup Report

The total has gone OVER in 5 of Tennessee's last 6 games

Minnesota is 5-1 SU in its last 6 games when playing at home against Tennessee

San Diego at New Orleans - Matchup Report

The total has gone OVER in 6 of San Diego's last 7 games when playing New Orleans

The total has gone OVER in 8 of New Orleans's last 9 games

Houston at NY Jets - Matchup Report

Houston is 5-1 SU in its last 6 games

NY Jets are 5-0 SU in their last 5 games when playing Houston