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NFL Opening Betting Lines: Week 16 Odds

The Seattle Seahawks trail the Arizona Cardinals by one game in the NFC West standings heading into Week 16 of the season, and they'll get a chance to close that division gap on Sunday Night Football as 7.5-point road favorites on the opening betting lines at the sportsbooks.

Arizona is 11-3 SU and 10-4 ATS on the season, while Seattle is 10-4 SU and 8-6 ATS - and riding a four-game SU winning streak. The Seahawks topped the Cardinals 19-3 as a 7.5-point home favorite in their first meeting of the season on November 23, and Seattle is 3-1 both SU and ATS in the last four games between the teams.

[ See the updated NFL Week 16 odds right now on the OddsShark NFL Odds page ]

Four other games take place outside of Sunday afternoon this week, including Tennessee at Jacksonville (-3) on Thursday night, Philadelphia at Washington (+8.5) on Saturday afternoon, San Diego at San Francisco (-2.5) on Saturday night, and Denver at Cincinnati (+3.5) on Monday night in a battle between a pair of division leaders.

Cincinnati heads into Week 16 with a slim lead in the AFC North at 9-4-1 SU, with both the Pittsburgh Steelers and the Baltimore Ravens at 9-5 SU through 14 games. The Steelers opened as 3-point home favorites against the Kansas City Chiefs for Week 16, while the Ravens opened as 3.5-point road favorites against the Houston Texans.

Matchup Reports: Seattle vs. Arizona | Indianapolis vs. Dallas | Atlanta vs. New Orleans

The NFC North division race is also tight, with 10-4 Green Bay opening as a 10-point road favorite against Tampa Bay for Week 16, and 10-4 Detroit opening as a 4.5-point road favorite against Chicago. The Lions are riding 3-0 SU and 4-0 ATS runs against the Bears heading into Week 16.

Elsewhere, the Dallas Cowboys opened as slim 1-point home favorites against the Indianapolis Colts for Sunday afternoon, with the New Orleans Saints opening as 6.5-point home favorites against the Atlanta Falcons, and the Carolina Panthers opening as 3.5-point home favorites against the Cleveland Browns.

Week 16 NFL Opening Betting Lines:

THURSDAY, DECEMBER 18
Tennessee at Jacksonville (-3), 8:25pm ET

SATURDAY, DECEMBER 20
Philadelphia at Washington (+8.5), 4:30pm ET
San Diego at San Francisco (-2.5), 8:25pm ET

SUNDAY, DECEMBER 21
Minnesota at Miami (-6.5), 1:00pm ET
Baltimore at Houston (+3.5), 1:00 pm ET
Detroit at Chicago (+4.5), 1:00pm ET
Cleveland at Carolina (-3.5), 1:00pm ET
Atlanta at New Orleans (-6.5), 1:00pm ET
Green Bay at Tampa Bay (+10), 1:00pm ET
Kansas City at Pittsburgh (-3), 1:00pm ET
New England at NY Jets (+10), 1:00pm ET
NY Giants at St. Louis (-5.5), 4:05pm ET
Buffalo at Oakland (+5.5), 4:25pm ET
Indianapolis at Dallas (-1), 4:25pm ET
Seattle at Arizona (+7.5), 8:30pm ET

MONDAY, DECEMBER 22
Denver at Cincinnati (+3.5), 8:30pm ET

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