Tyrod Taylor outplayed Andrew Luck in helping the Bills roll past the Colts at home, 27-14, last Sunday. Can Taylor now beat Tom Brady and visiting New England?
History says no. The Patriots have owned this series under Bill Belichick winning 21 of the last 23 meetings. New England also has covered in nine of their last 11 road games versus Buffalo.
Houston Texans coach Bill O'Brien doesn't want to tip his hand about which quarterback he's going to start at Carolina on Sunday, either Brian Hoyer or Ryan Mallet.
Like the Panthers are shaking in fear over the decision. The Panthers have won straight-up 12 of the past 13 times they have been a home favorite.
Vikings Back Home as Betting Favorites
The Minnesota Vikings showed they weren't ready for prime time in falling this past Monday night to the 49ers. Now the Vikings are home and 3-point favorites versus Detroit.
The Lions have failed to cover in nine of their last 11 road/neutral site regular season games. They also have lost nine of the last 11 times on the road to Minnesota.
It's easy to envision lots of points when thinking about Andrew Luck and Indianapolis. However, the under is 0-7-1 in the Colts' last eight games.
St. Louis is laying 3 1/2 at Washington. The last time the Rams were this big of a road favorite was 2010. The flip side is the Redskins are 2-10 against the spread (ATS) in their last 12 home games.
Cardinals 18-7 ATS in their last 25 games
Want another reason to like Arizona coach Bruce Arians? The Cardinals are 18-7 ATS in their last 25 games.
Jacksonville usually is bad every week. But the Jaguars have proven especially inept during Week 2 failing to cover eight straight seasons in their second game. The Jaguars have lost in Week 2 the past five years by an average of 23 points.
San Diego ventures to Cincinnati for an early Sunday start time. That's a negative for the West Coast Chargers, who are 1-8 ATS in their last nine AFC matchups.
Another negative for the Chargers is facing a Bengals squad that is 15-5-1 ATS in their last 21 games at Paul Brown Stadium.
