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NFL Week 7: Potential Upsets

For the second week in a row underdogs outdid the favorites in the NFL, going 8-7, with three of the pups winning outright. The favorites are 45-44-3 after the first six weeks of the season while 29 of the underdogs have won outright.

Four of this week's underdogs have not only been decent at the window when catching points, but they've also won a fair share of games outright. Arizona, Buffalo, Cincinnati and Indianapolis are a combined 12-4-1 ATS as an underdog, with nine of those covers being outright wins.

Arizona is +6 at home Thursday against Seattle at 5Dimes. On Sunday, Buffalo is +9 at Miami, Cincinnati is +2.5 at Detroit and Indianapolis, in the biggest spotlight game, is +7 at home against Denver.

The last time Seattle and Arizona met in an NFC West clash, the Seahawks dealt the Cardinals their worst loss in franchise history - a 58-0 beatdown. That was in Seattle; this game is in Glendale and the Cards figure to be much more competitive this time around. Arizona - 4-2 ATS as a dog with two outright wins - is 2-0 at home and undoubtedly will be fired up for this nationally televised game.

Like Arizona, the Bills are also 4-2 ATS as an underdog with two outright wins. They head to South Beach off a loss to Cincinnati, albeit an encouraging one. A pair of late touchdowns against the Bengals revealed that even with practice-squad quarterback Thad Lewis, the Bills' offense is capable.

Speaking of the Bengals, they're 2-0-1 as an underdog this season, and both covers were outright victories. They lead the AFC North on its own at 4-2 and come into this one having won their only previous game at Ford Field. They've beaten the Lions four straight times.

Finally, in the Sunday night game, the Colts look to make it three in a row when catching points, as they've won both games outright they were catching points. Sunday marks the first time Peyton Manning returns to Indy since he was released by the Colts and signed with Denver, and Luck's first time playing against him.