Spread favors Saints vs. the 49ers

The San Francisco 49ers are one of the few teams to have beaten the New Orleans Saints at home in recent seasons.

The 49ers went into New Orleans last year and knocked off the Saints. But that was without coach Sean Payton.

With Payton back on the sidelines, the Saints have been nearly unstoppable in the Superdome this season.

The Saints are 3-point home favorites over the 49ers. New Orleans has covered the spread in 21 of their last 26 home games and are on a 20-4 run against the spread as home chalk.

San Francisco has beaten the Saints in each of the past two seasons, including a thrilling playoff win in 2012. The 49ers are coming off a physical loss to the Carolina Panthers. The Saints blew out the Dallas Cowboys on Sunday night, setting a record with 40 first does in the game.

Backers of the Saints have seen them go 7-2 and 6-3 ATS so far this season, while the 49ers are at 6-3 and 6-3 ATS. In totals betting, the 49ers are 5-4, while the Saints are 5-4.

View San Francisco 49ers vs New Orleans Saints Odds and Stats.

The visitors opened as 2.5-point underdogs in this one at most sportsbooks tracked here at OddsShark (including Bovada), while the total was hovering around 47.5 at most shops (including BetOnline.

According to the Power Rankings here at OddsShark it's the No. 2-rated Saints and the No. 5-rated 49ers in this matchup. Predictive formulas point to a 31-28 win for the Saints on Sunday.

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Last time out for San Francisco, they were a 10-9 loser as they battled the Panthers at home. The 49ers failed to cover in the match as a 6-point favorite, while 19 combined points moved the game UNDER for totals bettors. Drew Brees dusted the Cowboys secondary for 4 TDs last time out as the Saints defeated Dallas 49-17 at Mercedes-Benz Superdome.

How They Match Up:
Offensively, the game matches up New Orleans's No. 2-ranked offense (29.44 PPG) against a 49ers defense that ranks No. 4 at 17.22 PPG. The Saints passing attack has averaged 324.89 yards per game, more than the 49ers give up through the air (211.44 YPG on average).

Defensively, the 49ers feature the league's No. 5-rated road run defense, allowing 87.5 yards per game. New Orleans, meanwhile, ranks No. 17 in rushing offense at home.

A few 49ers at Saints trends to consider:
San Francisco is 5-1 ATS in its last 6 games
San Francisco is 5-1 SU in its last 6 games
The total has gone OVER in 12 of San Francisco's last 16 games
San Francisco is 4-1 ATS in its last 5 games on the road
New Orleans is 5-2 ATS in its last 7 games
New Orleans is 7-2 SU in its last 9 games
The total has gone OVER in 5 of New Orleans's last 6 games
New Orleans is 5-0 ATS in its last 5 games at home

Next up:
San Francisco at Washington, Monday, November 25th
New Orleans at Atlanta, Thursday, November 21st