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Colts hold off Jaguars

Peyton Manning threw for 288 yards with four touchdowns Sunday, as the Indianapolis Colts defeated the Jacksonville Jaguars 28-25.

The Colts had been favored by 6.5-points in the game and were unable to cover the spread. The combined score went OVER the posted over/under total (45).

Reggie Wayne caught eight passes for 158 yards with a touchdown for the Colts, while Dallas Clark caught seven passes for 60 yards and two touchdowns.

David Garrard completed 24-of-29 passes for 257 yards with two touchdowns and an interception for Jacksonville, while Fred Taylor rushed for 104 yards on 14 carries.