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Red Sox host the Orioles at Fenway Park

The Baltimore Orioles will be turning to their ace on Friday night at Fenway Park as they open up an MLB betting series against the division-rival Boston Red Sox at the sportsbooks.

Chris Tillman is slated to get the ball for Baltimore on Friday, and he's 1-1 with an 0.84 ERA through his first three starts of the season. The righthander is also 4-2 with a 2.67 ERA over his 12 career starts against the Red Sox.

John Lackey (2-1, 3.86 ERA) will be on the mound for the Red Sox on Friday night.

Baltimore Orioles vs Boston Red Sox Opening Odds and Betting Line

The moneyline was hovering in the range of -139 for the Boston Red Sox in this one over at TopBet. The over under number was sitting near 8 at 5Dimes.

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Computer Prediction: Baltimore Orioles vs Boston Red Sox Pick

Odds Shark computer prediction formulas pick a 3.8-3.6 win for the Orioles on Friday. Odds Shark score prediction models pick a 3.8-3.6 result in favor of the Orioles today. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Baltimore Orioles vs Boston Red Sox Odds and Stats.

Team Betting Records & Power Rankings

7-9 Boston battles the Orioles, currently with a 7-7 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and Boston vs Baltimore injuries news.

This game puts the Boston Red Sox, most recently No. 15 in Odds Shark MLB Power Rankings, up against the Baltimore Orioles, who rate a No. 25 in the latest survey.

How Baltimore Orioles vs Boston Red Sox Stats Matchup

On offense, it's a battle between the Boston Red Sox and its No. 25-rated batting order, averaging 3.5 runs per nine innings, against the No. 20 lineup of the Baltimore Orioles at 4 runs per outing.

Boston owns the No. 10 defense, allowing 3.5 men per game to cross the plate. That contrasts with Baltimore's No. 16-rated defense.

Recent Outings Betting Recap

The Orioles were a 3-0 winner in their most recent outing at home against the Rays. Baltimore threw a shutout at Tampa Bay in their last outing, using a shutdown performance by Miguel Gonzalez to defeat Tampa Bay 3-0 on Wednesday.

Boston won its last outing, a 3-1 result against the White Sox on April 17. Bettors who backed the Red Sox at +100 on the moneyline won on the day, and the total score (4) sent UNDER bettors to the payout window. Boston got the job done in their last match in a 3-1 victory over Chicago on Thursday at U.S. Cellular Field behind starter Jon Lester.

Next Betting Matchups

Baltimore at Boston, Saturday, April 19th