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The Chicago Cubs take on the Boston Red Sox on Saturday night.

The Boston Red Sox (43-34) visit the Chicago Cubs (31-46) at Wrigley Field on Saturday as the clubs face off in the second meeting of a three-game set. The Red Sox are 8-3 in their last 11 outings while the Cubs are 4-1 in their last five contests. Find out if Chicago can win its fourth straight game in our Red Sox vs Cubs prediction.

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Red Sox vs Cubs Opening Odds Analysis

Opening Odds

The Red Sox and Cubs both opened at -116 the moneyline in a true pick ‘em. The total was set at ? runs with the OVER going 4-1 in both Boston and Chicago’s last five contests. Chicago is 5-2 in the last seven meetings against Boston, which may give the hosts a slight edge in your Red Sox vs Cubs prediction.

Starting Pitchers 

Alec Mills (0-1) will make his seventh appearance and second start of the season for the Cubs. The right-hander lasted just 2.2 innings last time out in his start against the St. Louis Cardinals on June 26 after surrendering six hits and five earned runs. Mills has a lofty 9.87 ERA and a 1.73 ERA over 17.1 innings this season.

The Red Sox will send Josh Winckowski (3-1) to the mound for his fifth start of the year.  Winckowski picked up his third straight win on June 25 when he held the Cleveland Guardians to six hits and two earned runs over 5.1 innings. The rookie owns a 3.60 ERA and a 1.45 WHIP over 20 innings of work. 

Get the best Red Sox vs Cubs odds and lines available from our recommended sportsbooks for your favorite picks of the night.

  • Best Spread
    +110
    -125
    BOS-1.5
    +1.5CHC
  • Best Moneyline
    -138
    +138
    BOS
    CHC
  • Best Total
    +105
    -120
    Over9.5
    9.5Under

Red Sox Blow Lead In Series Opener

Boston fell just short in the series opener as Chicago took Friday’s matchup by a score of 6-5. The Red Sox got out to an early lead thanks to a solo shot from Jarren Duran in the first followed by a three-run homer from Jackie Bradley Jr. in the second. Duran added another RBI in the sixth to make it 5-3 Red Sox but that’s all the offense Boston could muster as Chicago rallied for a comeback win.

While the Red Sox had their seven-game win streak snapped by the Toronto Blue Jays back on June 28, the run allowed Boston to surge up the standings, now sitting one game back of Toronto for the top wild card spot in the American League. Only two clubs in the American League have more wins than Boston over their last 10 outings: the Houston Astros (8-2) and Seattle Mariners (8-2).

Cubs Look To Win Fourth Straight On Saturday

The Cubs scored all six of their runs in the fifth and sixth innings to take the series opener against the Red Sox on Friday. Nelson Velazquez got the party started in the fifth with an RBI triple before Christopher Morel knocked in a run and Rafael Ortega took a bases-loaded walk. The offense continued in the sixth as Morel hit a two-run shot and Willson Contreras scored the eventual game-winning run on a wild pitch.

Chicago earned its third straight victory, just one shy of the club’s longest win streak of the season when the Cubs won four straight from May 14-17. The Cubs are averaging a whopping 9.67 runs per game over their current win streak, thanks in large part to a 15-run outburst against the Cincinnati Reds on June 30.

Red Sox vs Cubs Pick & Insights

Red Sox: Keys To Victory

Despite losing three of their last four games, the Red Sox are still one of the hottest teams in the majors and should feel confident going into Saturday’s matchup. Winckowski may be inexperienced but the 24-year-old has been solid through his last three starts, allowing just four earned runs in 17 innings over that span. If Winckowski can keep up that level of play, Boston will be in great shape.

Cubs: Keys To Victory

The Cubs have a struggling arm on the mound in Mills, who hasn’t been used much in a starting role this season. Chicago will hope that their hot bats can outscore any pitching problems, with Morel leading the way. The center fielder has homered in three straight contests, racking up seven RBI and eight hits along the way.

MLB Computer Pick: Red Sox -140 ML

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Shark Bites
  • Boston is 13-5 in its last 18 road games.
  • Boston is 14-6 in its last 20 games vs. the NL.
  • Chicago is 1-5 in its last 6 games vs. the AL.