Chicago will try to be nasty hosts on Wednesday when the Boston Red Sox pay a visit to U.S. Cellular Field.

Hector Santiago gets the call for the Chicago White Sox and he will try to build on a 1-1 mark. In the other dugout, Clay Buchholz brings a 6-0 ledger to the game for the Red Sox as he tries to quiet the White Sox bats.



View Boston vs Chi White Sox Odds and Stats.

Betting Line:
Those going with the White Sox in this one found them listed as moneyline favorites of -119 at Sportsbook for Monday's contest. The total was hovering near 7.5 at Sportsbook.

Power Rankings:
The Odds Shark MLB Power Rankings have the White Sox at No. 11 in the American League and the Red Sox at No. 2 in the American League heading into this contest.



How They Match Up:
Scoring stats point to some edges in this matchup. The game features Chicago's American League No. 14-ranked scoring average of 3.7 runs per game, against a Red Sox offense rated No. 5 and scoring 4.8 runs per game in the league. The White Sox have averaged 8.1 hits per game to date this season, less than the Red Sox hitters have managed (8.9 per nine innings).

Comparing defensive stats, Boston owns the American League's No. 2-rated road mark, allowing 3.5 runs per game on the highway. Chicago, on the other hand, rates No. 15 in scoring at home.

Last time out for Boston, they were a 3-1 loser as they battled the White Sox on the road. Moneyline bettors who got the White Sox at -103 were rewarded, while the 4 combined runs moved the game UNDER for totals bettors. Boston suffered a 3-1 loss against Chicago on Tuesday, as Felix Doubront wasn't able to lead his team to victory at U.S. Cellular Field.




Boston Red Sox Trends:
When playing on Wednesday are 3-7
Before playing Cleveland are 6-4
After playing Chi White Sox are 5-5
After a loss are 3-7

Chicago White Sox Trends:
When playing on Wednesday are 4-6
Before playing Miami are 5-4
After playing Boston are 4-6
After a win are 5-5

A few Red Sox at White Sox trends to consider:
Boston is 5-2 SU in its last 7 games
Boston is 5-2 SU in its last 7 games on the road
The total has gone UNDER in 4 of Boston's last 6 games
The total has gone UNDER in 4 of Boston's last 6 games on the road
Chi White Sox are 6-2 SU in their last 8 games
The total has gone OVER in 5 of Chi White Sox's last 7 games
Chi White Sox are 4-8 SU in their last 12 games when playing Boston


Next up:
Boston home to Cleveland, Thursday, May 23
Chi White Sox home to Miami, Friday, May 24