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Chicago Cubs vs San Diego Padres Betting Pick and Odds Preview

The San Diego Padres will look to improve on a 20-20 record when they take on the Chicago Cubs, a key part of the MLB betting odds line up on Wednesday.

Chicago puts its faith in starter Tsuyoshi wada to earn a win and boost his personal mark of 0-0. Getting the ball for the San Diego Padres is Tyson Ross, who owns a 2-3 record on the season with a 3.94 ERA.

Opening Odds & Computer Pick

San Diego was a -137 moneyline favorites earlier in the day at BetOnline, based on the starting pitcher matchup. That pairing made odds makers at 5Dimes pick an opening over under number of 7.

Odds Shark computer prediction handicapping models run on this game pick a 4.5-3.9 victory for the Cubs. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Chicago Cubs vs San Diego Padres Matchup

Team Betting Records & Power Rankings

The San Diego Padres sport a record of 20-20 heading into this matchup, while the Chicago Cubs sit at 21-17 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and San Diego vs Chicago injuries news.

The San Diego Padres vs Chicago Cubs odds would favor the Cubs if the betting lines were set according to our power ranks. San Diego is rated No. 29 in the current Odds Shark poll, while Chicago is at No. 22.

Statistical Matchup

Scoring stats point to some edges in this matchup. The game features the San Diego Padres No. 9-ranked scoring average of 4.47 runs per game, against a Chicago Cubs offense rated No. 14 and scoring 4.29 runs per game. The Padres have averaged 8.62 hits per game to date this season, more than the Cubs hitters have managed (8.47 per nine innings).

Chicago brings the No. 14-rated defense to this matchup, facing the Padres's No. 27-ranked defense.

Recent Outings Betting Recap

Chicago batters were mowed down by James Shields in their last start, falling 4-3 against San Diego while striking out 11 times on Tuesday at PETCO Park.

Betting Trends
  • Chi Cubs is 6-2 SU in its last 8 games
  • Chi Cubs is 1-4 SU in its last 5 games on the road
  • The total has gone OVER in 6 of Chi Cubs's last 8 games on the road
  • Chi Cubs is 1-5 SU in its last 6 games when playing San Diego
  • The total has gone OVER in 4 of San Diego's last 5 games
  • The total has gone OVER in 5 of San Diego's last 6 games at home
  • San Diego is 5-1 SU in its last 6 games when playing Chi Cubs
  • The total has gone OVER in 5 of San Diego's last 6 games when playing Chi Cubs

Next Betting Matchups

Chicago at San Diego, Thursday, May 21st