Corey Kluber, Tyler Skaggs Take Mound in Cleveland Indians vs Los Angeles Angels Tilt

The Los Angeles Angels look to emerge victorious in MLB odds action as the Cleveland Indians arrive at Angel Stadium on Wednesday.

The Los Angeles Angels will turn to Tyler Skaggs and his 1-0 record as they look for a win in this one, while the Cleveland Indians send Corey Kluber (0-1) to the hill.

Sportsbook Odds & Computer Pick

The visiting Cleveland Indians were -149 moneyline favorites in this one earlier in the day at most online sportsbooks including Sportsbook. The total was 7.5 at Sportsbook for those preferring over under betting.

Odds Shark computer prediction formulas pick a 4.1-2.7 win for the Angels on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Cleveland Indians vs Los Angeles Angels Matchup

Team Betting Records & Power Rankings

The Los Angeles Angels sport a record of 4-2 heading into this matchup, while the Cleveland Indians sit at 2-3 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Los Angeles vs Cleveland injuries news.

According to MLB Power Rankings here, it's the No. 16-ranked Los Angeles Angels and the No. 5-rated Cleveland Indians in this matchup.

Statistical Matchup

On offense, it's a battle between the Los Angeles Angels and its No. 7-rated batting order, averaging 5.83 runs per nine innings, against the No. 20 line up of the Cleveland Indians at 3.8 runs per outing.

Pitching and defensive stats are important baseball handicapping betting factors and Los Angeles has the No. 6-ranked defense. In the other dugout, the Indians own the No. 20 mark in runs allowed.