Chicago White Sox Favored by -127 Against Detroit Tigers on Wednesday

The visiting Detroit Tigers hope for a solid performance on Wednesday as they look to pick up a win at U.S. Cellular Field against the Chicago White Sox.

Chicago sends Jose Quintana out against Anibal Sanchez for the Detroit Tigers in this game. Quintana is 11-10 with a 3.04 ERA on the season, while Sanchez is 7-13 on the year and has a 5.70 ERA.

Sportsbook Odds & Computer Pick

Betting fans looking to pick the visiting Detroit Tigers before the first pitch in this match found them as 117 moneyline underdogs earlier today at Sportsbook. They saw the over/under total of 9 earlier at Sportsbook.

Handicapping models based on recent betting stats and prediction formulas pick a 5.4-4.9 win for the Tigers. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Detroit Tigers vs Chicago White Sox Matchup

Team Betting Records & Power Rankings

The Chicago White Sox sport a record of 66-72 heading into this matchup, while the Detroit Tigers sit at 75-63 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs Detroit injuries news.

This game matches up the No. 15 (Chicago White Sox) and the No. 6 (Detroit Tigers) teams, according to our current MLB Power Rankings.

Statistical Matchup

Offensively, the game matches up Chicago White Sox No. 25 ranked offense (4.14 runs per game) against a Detroit Tigers defense and pitching staff that sits at No. 16 at 4.45 runs allowed per game. The Chicago White Sox have been averaging 8.72 hits per game, less than the Detroit Tigers have managed so far this season (9.19 hits on average).

Defensively, Detroit features the No. 14-rated defense on the road, allowing 4.61 runs per game. Chicago, meanwhile, comes in at No. 24 at home, scoring 4.09 runs per game.