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Felix Doubront vs Barry Zito matchup featured in MLB action

Boston Red SoxSan Francisco Giants
Aug 21, 3:45 PM | GrassAT&T Park

Boston Red Sox vs San Francisco Giants Odds

74-54TEAM RECORD56-69

San Francisco's pitching staff and batting order hope to create an unwelcoming environment in interleague play on Wednesday when the Boston Red Sox pay a visit to AT&T Park.

San Francisco sends Barry Zito out against Felix Doubront for the Red Sox in this game. Zito is 4-8 with a 5.09 ERA on the season, while Doubront is 8-6 on the year and has a 3.69 ERA.

View Boston vs San Francisco Odds and Stats.

Betting Line:
Bettors looking to side with the Giants in this matchup found them as +125 underdogs on the MLB money line at 5Dimes. Betting the over under instead? It was 7.5 at its open earlier today and hovering near that number at Sportsbook.ag.

Power Rankings:
It's a baseball betting matchup between the National League No. 7-rated Giants and the league No. 3-ranked Red Sox, according to the latest MLB power poll here at Odds Shark.

How They Match Up:
At the plate, San Francisco owns the No. 5 ranking for hits in the National League at 8.9 per game. By contrast, the Red Sox are rated No. 2 in the same category at 9.5 per game.

Pitching and defensive stats are important baseball handicapping factors and San Francisco has the National League's No. 12-ranked defense. In the other dugout, the Red Sox own the American League's No. 7 mark in runs allowed.

Boston lost its last outing, a 3-2 result against the Giants on August 20. Bettors who backed the Giants at +148 on the moneyline won on the day, and the total score (5) sent UNDER bettors to the payout window. The Red Sox endured a 3-2 loss at the hands of the Giants on Tuesday, with Jake Peavy throwing 5 2/3 innings of 5-hit ball at AT&T Park.

Boston Red Sox Trends:
When playing on Wednesday are 4-6
Before playing LA Dodgers are 6-3
After playing San Francisco are 6-4
After a loss are 7-3

San Francisco Giants Trends:
When playing on Wednesday are 7-3
Before playing Pittsburgh are 6-4
After playing Boston are 4-6
After a win are 4-6

A few Red Sox at Giants trends to consider:
The total has gone UNDER in 6 of Boston's last 7 games on the road
Boston is 6-2 SU in its last 8 games when playing San Francisco
The total has gone UNDER in 7 of Boston's last 10 games
The total has gone UNDER in 4 of Boston's last 6 games when playing on the road against San Francisco
San Francisco is 4-2 SU in its last 6 games
The total has gone UNDER in 8 of San Francisco's last 12 games at home
The total has gone UNDER in 4 of San Francisco's last 6 games when playing at home against Boston
San Francisco is 4-12 SU in its last 16 games at home

Next up:
Boston at LA Dodgers, Friday, August 23
San Francisco home to Pittsburgh, Thursday, August 22