Astros vs Red Sox Pick

Astros vs Red Sox Odds & Betting: Houston A Dog Despite Recent Dominance

The Houston Astros (23-12) are 9-4 in their last 13 games against the Boston Red Sox (13-21). The Astros will look to continue their current hot streak and their recent success against the Red Sox with a win as an Astros vs Red Sox prediction underdog Monday night in Boston.

Best MLB Betting Sites

Astros vs Red Sox Betting Preview

Astros vs Red Sox Odds & Analysis

Sportsbook Odds

The Red Sox opened as -120 favorites before the line settled in at Boston -125. Houston is currently listed as a +105 road underdog while Astros vs Red Sox predictions on the OVER have bumped the total up to 9 runs after it opened at 8.5 runs. The OVER is 5-0 in Houston’s last five road games against Boston.

Get the best Astros vs Red Sox odds and lines available from our recommended sportsbooks for your favorite picks of the night.

  • Best Spread
    -172
    +152
    HOU+1.5
    -1.5BOS
  • Best Moneyline
    +114
    -124
    HOU
    BOS
  • Best Total
    -125
    +105
    Over9
    9Under

Starting Pitchers

Jake Odorizzi has pitched 11.2 scoreless innings so far in May with 6.2 shutout innings in a 3-0 win over the Seattle Mariners on May 2 and five shutout innings in a 5-0 win over the Detroit Tigers on May 8. Odorizzi carries a 3.38 ERA and a 1.24 WHIP into Monday night’s start against Boston.

Garrett Whitlock has moved into Boston’s starting rotation after Sportsbook the season in the bullpen. Through 24.2 innings pitched across four starts and four bullpen appearances, Whitlock has recorded a 2.19 ERA and a 0.93 WHIP with 34 strikeouts.

Houston’s Pitching Has Been Exceptional During Recent Surge

The Astros bounced back from a 13-6 loss to the Washington Nationals on Saturday with an 8-0 shutout win to close out the series on Sunday. Before allowing those 13 runs on Saturday, Houston had gone 11-0 over its previous 11 games while allowing only 1.09 runs per game.

Houston suffered through a 3-8 slump in mid-April, but since then the Astros are 16-3 over their last 19 games. Bettors taking Houston as their Astros vs Red Sox prediction will be looking for another strong game on the mound in this series opener.

Boston Looked A Bit Better Last Week After Long Slump

The Red Sox fell short of sweeping the Texas Rangers with a 7-1 loss on Sunday, but they still managed to win the three-game series after rolling to a 7-1 win on Friday and an 11-3 win on Saturday. Boston is now 3-2 over its last five games since going 3-12 over its previous 15.

An underwhelming season from the offense has contributed to Boston’s early-season struggles. The Red Sox pitching staff and bullpen have been right around the middle of the pack with a 3.75 team ERA while the offense ranks 23rd in the majors in averaging 3.70 runs per game.

Astros vs Red Sox Pick & Insights

Astros: Keys To Victory

Houston’s pitching has been nearly unhittable over the last two weeks and the offense is clicking too, averaging 6.57 runs per game over the team’s last seven games. The Astros should be a pretty popular Astros vs Red Sox prediction getting underdog odds given the way they are playing.

Red Sox: Keys To Victory

Jake Odorizzi owns an underwhelming 4.87 ERA and a 1.35 WHIP in 20 career starts against the Red Sox. Boston’s offense showed some life over the weekend, and getting to Odorizzi will be the key to securing a win as an Astros vs Red Sox pick at home.

MLB Computer Pick: Astros +105

Check out more of our signature MLB computer picks, plus our favorite sportsbooks that serve baseball customers.

Shark Bites
  • Houston is 10-0 in its last 10 games vs AL teams.
  • Boston is 0-5 in its last 5 home games.
  • The OVER is 7-1 in Boston’s last 8 games vs Houston.
Back to Top