Pittsburgh Pirates vs San Francisco Giants MLB Baseball Betting Lines Preview

Those betting on MLB baseball odds will look to pick a Sportsbook at AT&T Park on Wednesday as the host San Francisco Giants battle the Pittsburgh Pirates in baseball betting odds action.

The San Francisco Giants will rely on Matt Cain to turn in a quality outing on the mound in this one, while Ivan Nova will be his counterpart for the Pittsburgh Pirates. Matt Cain is 4-7 this season, and Ivan Nova is 9-6.

Sportsbook Odds & Computer Pick

Baseball betting odds makers, including Sportsbook, opened the San Francisco Giants as -125 moneyline favorites in this matchup. Over under total bettors saw the number open at 8 at shops such as Sportsbook.

Prediction-scoring formulas run on this game pick a potential 5.6-4.4 result in favor of the Pirates. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

Pittsburgh Pirates vs San Francisco Giants Matchup

Team Betting Records & Power Rankings

The San Francisco Giants bring a 66-53 record to the battle against the 61-56 Pirates. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs Pittsburgh injuries news.

The San Francisco Giants sit at No. 16 in the current MLB power poll here at Odds Shark, while the Pittsburgh Pirates sit at No. 12 on the same chart.

Statistical Matchup

When it comes to getting on base, the visiting Pittsburgh Pirates rank No. 13 at 8.84 hits per game. That compares with the San Francisco Giants No. 11 ranking in that category.

San Francisco owns the No. 6 defense, allowing 4.44 men per game to cross the plate. That contrasts with Pittsburgh's No. 18-rated defense.