San Diego Padres visit Chicago Cubs in MLB Betting Odds Clash

The Chicago Cubs get a visit from the San Diego Padres in MLB baseball betting action on Wednesday, with the home side looking to send the visitors to the showers with a loss.

The match puts starter Colin Rea for the San Diego Padres on the hill facing Kyle Hendricks for the Chicago Cubs. Rea brings a 3-1 mark to the game, while Hendricks is 2-2 to date on the season.

Handicapping models based on recent betting stats and prediction formulas pick a 6.2-2.7 win for the Cubs. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs Chicago Cubs Matchup

Team Betting Records & Power Rankings

25-6 Chicago battles the Padres, currently with a 13-20 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs San Diego injuries news.

The Chicago Cubs sit at No. 1 in the current MLB power poll here at Odds Shark, while the San Diego Padres sit at No. 23 on the same chart.

Statistical Matchup

On offense, it's a battle between the Chicago Cubs and its No. 1-rated batting order, averaging 6.19 runs per nine innings, against the No. 24 line up of the San Diego Padres at 3.73 runs per outing.

Pitching and defensive stats are important baseball handicapping betting factors and Chicago has the No. 1-ranked defense. In the other dugout, the Padres own the No. 19 mark in runs allowed.