The San Diego Padres host San Francisco on Wednesday, looking to build on their 61-80 mark against the 74-67 Giants in MLB betting action at PETCO Park.

San Diego hands the ball to starter Aaron Harang in this one and he'll try to improve on his 12-5 mark on the year. San Francisco counters with Matt Cain, who will try to quiet the fans and the Padres bats at the same time.



View San Francisco vs San Diego Odds and Stats.

Betting Line:
The Padres were listed as +130 moneyline underdogs at most sportsbooks tracked by Odds Shark, while oddsmakers set the Sportsbook total around 6 earlier on Monday.

Power Rankings:
The Padres - Giants odds would favor the Giants if the lines were set according to our power ranks. San Diego is rated No. 11 in the current National League Odds Shark poll, while San Francisco is at No. 5 in the National League.



How They Match Up:
The game also pits San Diego's No. 15-rated National League offense, averaging 3.7 runs per game, against a Giants defense that ranks No. 2 in the National League at 3.5 in runs allowed per game. The Padres have averaged 8 hits per game so far, almost the same as Giants batters have averaged on the year (8 hits per game).

San Diego owns the National League's No. 5 defense, allowing 3.9 men per game to cross the plate. That contrasts with San Francisco's National League No. 2-rated defense.

Last time out for San Francisco, they were a 6-4 Sportsbook as they battled the Padres on the road. Moneyline bettors who got the Giants at -106 were rewarded, while the 10 combined runs moved the game OVER for totals bettors. San Francisco rolled to a 6-4 win against San Diego on Tuesday, as Eric Surkamp and the Giants' bats led the team to victory at PETCO Park.

Next up:
San Francisco home to LA Dodgers, Friday, September 9
San Diego at Arizona, Thursday, September 8