San Diego Padres at San Francisco Giants Betting Odds and Pick

MLB wagering interest swings to the San Diego Padres vs San Francisco Giants battle on Monday at AT&T Park as the Giants try to pick up a win on home turf and reward those moneyline betting.

It's a pitching duel between Jeff Samardzija for the San Francisco Giants (1-1 on the year) and Eric Lauer for San Diego Padres (0-1 so far).

Sportsbook Odds & Computer Pick

Sportsbooks such as Sportsbook had set the San Francisco Giants as -170 favorites on the moneyline for this contest. The over under was hovering near 8 for betting fans hoping to turn a profit on totals at Sportsbook.

Handicapping models based on recent betting stats and prediction formulas pick a 4.3-2.4 win for the Giants. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs San Francisco Giants Matchup

Team Betting Records & Power Rankings

14-14 San Francisco battles the Padres, currently with a 10-19 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs San Diego injuries news.

This game puts the San Francisco Giants, most recently No. 20 in Odds Shark MLB Power Rankings, up against the San Diego Padres, who rate a No. 25 in the latest survey.

Statistical Matchup

When it comes to getting on base, the visiting San Diego Padres rank No. 23 at 7.76 hits per game. That compares with the San Francisco Giants No. 19 ranking in that category.

San Francisco owns the No. 10 defense, allowing 3.57 men per game to cross the plate. That contrasts with San Diego's No. 24-rated defense.