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MLB Odds with Pick - San Diego Padres vs San Francisco Giants

The San Francisco Giants host San Diego on Wednesday, looking to pick up a win and improve their 38-34 mark against the 35-38 Padres in MLB betting odds action at AT&T Park.

San Francisco hands the ball to starter Ryan Vogelsong in this one and he'll try to improve on his 5-5 mark on the year. San Diego counters with Ian Kennedy, who will try to quiet the fans and the Giants bats at the same time.

Opening Odds & Computer Pick

Betting fans looking to pick the San Francisco Giants in this matchup found them as -134 favorites on the MLB money line at BetOnline. Betting the over under instead? It was 7.5 at its open earlier today and hovering near that number at Bovada.

Odds Shark computer prediction formulas pick a 4.1-4 win for the Giants on Wednesday. Odds Shark score prediction models pick a 4.1-4 result in favor of the Giants today. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs San Francisco Giants Matchup

Team Betting Records & Power Rankings

38-34 San Francisco battles the Padres, currently with a 35-38 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs San Diego injuries news.

According to MLB Power Rankings here, it's the No. 18-ranked San Francisco Giants and the No. 24-rated San Diego Padres in this matchup.

Statistical Matchup

On offense, it's a battle between the San Francisco Giants and its No. 20-rated batting order, averaging 4.04 runs per nine innings, against the No. 14 line up of the San Diego Padres at 4.16 runs per outing.

Pitching and defensive stats are important baseball handicapping betting factors and San Francisco has the No. 9-ranked defense. In the other dugout, the Padres own the No. 25 mark in runs allowed.

Recent Outings Betting Recap

San Diego won a close affair on Tuesday in their last outing, defeating San Francisco 3-2 in extra innings at AT&T Park.

Betting Trends
  • San Diego is 3-6 SU in its last 9 games
  • The total has gone OVER in 18 of San Diego's last 25 games
  • San Diego is 5-2 SU in its last 7 games when playing San Francisco
  • San Diego is 2-4 SU in its last 6 games when playing on the road against San Francisco
  • San Francisco is 4-8 SU in its last 12 games
  • San Francisco is 1-10 SU in its last 11 games at home
  • The total has gone UNDER in 5 of San Francisco's last 6 games at home
  • San Francisco is 2-5 SU in its last 7 games when playing San Diego

Next Betting Matchups

San Diego at San Francisco, Thursday, June 25th