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San Diego Padres vs San Francisco Giants Betting Odds Preview and Pick

The San Francisco Giants host San Diego on Wednesday, looking to pick up a win and improve their 29-19 mark against the 19-28 Padres in MLB betting odds action at AT&T Park.

Jake Peavy gets the call for the San Francisco Giants and he will try to build on a 1-5 mark. In the other dugout, James Shields brings a 2-6 ledger to the game for the San Diego Padres as he tries to quiet the Giants bats.

Opening Odds & Computer Pick

Those going with the San Francisco Giants in this one found them listed on the odds board as moneyline favorites of -158 at BetOnline for Wednesday's contest. The betting total was hovering near 8 at Bovada.

Odds Shark computer prediction formulas pick a 5.3-1.5 win for the Giants on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs San Francisco Giants Matchup

Team Betting Records & Power Rankings

29-19 San Francisco battles the Padres, currently with a 19-28 mark. Stay Informed: follow us on Twitter for odds specials, betting line moves and San Francisco vs San Diego injuries news.

It's a MLB baseball betting matchup between the No. 13-rated San Francisco Giants and the league No. 24-ranked San Diego Padres, according to the latest MLB power poll here at Odds Shark.

Statistical Matchup

The game also pits San Francisco Giants No. 14-rated offense, averaging 4.31 runs per game, against a San Diego Padres defense that ranks No. 18 at 4.3 in runs allowed per game. The San Francisco Giants have averaged 8.62 hits per game so far, more than San Diego Padres batters have averaged on the year (7.43 hits per game).

San Francisco owns the No. 12 defense, allowing 4.31 men per game to cross the plate. That contrasts with San Diego's No. 18-rated defense.

Recent Outings Betting Recap

The Padres were saddled with a loss last time out in A Cashner's start, as they lost 8-2 against San Francisco on Tuesday at AT&T Park.

Betting Trends
  • San Diego is 2-7 SU in its last 9 games
  • The total has gone UNDER in 9 of San Diego's last 13 games
  • San Diego is 1-4 SU in its last 5 games on the road
  • The total has gone UNDER in 5 of San Diego's last 7 games on the road
  • San Francisco is 12-1 SU in its last 13 games
  • The total has gone UNDER in 13 of San Francisco's last 17 games
  • San Francisco is 5-1 SU in its last 6 games at home
  • The total has gone OVER in 4 of San Francisco's last 6 games at home

Next Betting Matchups

San Diego at Arizona, Friday, May 27th
San Francisco at Colorado, Friday, May 27th