OddsShark Top Sportsbooks

*Terms and Conditions apply to all bonus offers on this website. Please visit operator for details.

San Diego Padres vs St. Louis Cardinals Betting Odds Preview and Pick

The St. Louis Cardinals look to emerge victorious in MLB odds action as the San Diego Padres arrive at New Busch Stadium on Wednesday.

St. Louis hands the ball to starter Luke Weaver in this one and he'll try to improve on his 1-1 mark on the year. San Diego counters with Jhoulys Chacin, who will try to quiet the fans and the Cardinals bats at the same time.

Opening Odds & Computer Pick

The San Diego Padres were listed as 144 underdogs on the MLB baseball moneyline at many online sportsbooks, including Bet365. The total was set at 9 before betting started earlier on Wednesday over at Bovada.

Odds Shark computer score prediction models pick a possible 3.8-3.5 win for the Padres on Wednesday. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Diego Padres vs St. Louis Cardinals Matchup

Team Betting Records & Power Rankings

St. Louis (63-62) will face the 56-69 Padres in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and St. Louis vs San Diego injuries news.

It's a MLB baseball betting matchup between the No. 5-rated St. Louis Cardinals and the league No. 27-ranked San Diego Padres, according to the latest MLB power poll here at Odds Shark.

Statistical Matchup

Scoring stats point to some edges in this matchup. The game features the St. Louis Cardinals No. 16-ranked scoring average of 4.73 runs per game, against a San Diego Padres offense rated No. 30 and scoring 3.86 runs per game. The Cardinals have averaged 8.84 hits per game to date this season, more than the Padres hitters have managed (7.78 per nine innings).

Defensively, San Diego features the No. 29-rated defense on the road, allowing 5.6 runs per game. St. Louis, meanwhile, comes in at No. 18 at home, scoring 4.49 runs per game.

Recent Outings Betting Recap

The Padres grabbed a win last time out, defeating L Lynn and the Cardinals 12-4 on Tuesday at New Busch Stadium.

Betting Trends
  • The total has gone UNDER in 4 of San Diego's last 6 games
  • San Diego is 2-4 ATS in its last 6 games on the road
  • San Diego is 2-4 SU in its last 6 games on the road
  • The total has gone OVER in 8 of San Diego's last 9 games on the road
  • St. Louis is 1-4 ATS in its last 5 games
  • St. Louis is 2-6 SU in its last 8 games
  • The total has gone OVER in 13 of St. Louis's last 15 games
  • St. Louis is 3-7 ATS in its last 10 games at home

Next Betting Matchups

San Diego at St. Louis, Thursday, August 24th