San Francisco Giants vs Chicago Cubs Betting Odds Preview and Pick

The Chicago Cubs look to emerge victorious in MLB odds action as the San Francisco Giants arrive at Wrigley Field on Friday.

The Chicago Cubs will rely on Kyle Hendricks to turn in a quality outing on the mound in this one, while Derek Holland will be his counterpart for the San Francisco Giants. Kyle Hendricks is 3-3 this season, and Derek Holland is 2-5.

Handicapping models based on recent betting stats and prediction formulas pick a 5.8-2.8 win for the Cubs. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs Chicago Cubs Matchup

Team Betting Records & Power Rankings

The Chicago Cubs bring a 25-21 record to the battle against the 24-26 Giants. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs San Francisco injuries news.

According to MLB Power Rankings here, it's the No. 5-ranked Chicago Cubs and the No. 19-rated San Francisco Giants in this matchup.

Statistical Matchup

Scoring stats point to some edges in this matchup. The game features the Chicago Cubs No. 3-ranked scoring average of 5.17 runs per game, against a San Francisco Giants offense rated No. 20 and scoring 4.08 runs per game. The Cubs have averaged 9.09 hits per game to date this season, more than the Giants hitters have managed (8.94 per nine innings).

San Francisco brings the No. 23-rated defense to this matchup, facing the Cubs's No. 8-ranked defense.

Recent Outings Betting Recap

The Giants were saddled with a loss last time out in J Samardzija 's start, as they lost 4-1 against Houston on Wednesday at Minute Maid Park.

Adam Plutko shut down the Cubs in their last game, striking out 4 in a 1-0 shutout over Chicago in baseball action at Wrigley Field.

Betting Trends
  • San Francisco is 2-5 ATS in its last 7 games
  • San Francisco is 2-5 SU in its last 7 games
  • San Francisco is 2-7 ATS in its last 9 games on the road
  • San Francisco is 1-8 SU in its last 9 games on the road
  • Chi Cubs is 3-7 ATS in its last 10 games
  • Chi Cubs is 1-4 ATS in its last 5 games at home
  • Chi Cubs is 1-4 SU in its last 5 games at home
  • The total has gone OVER in 5 of Chi Cubs's last 7 games at home

Next Betting Matchups

San Francisco at Chicago, Saturday, May 26th

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