MLB Odds with Pick - San Francisco Giants vs Chicago Cubs

Those betting on MLB baseball odds will look to pick a Sportsbook at Wrigley Field on Thursday as the host Chicago Cubs battle the San Francisco Giants in baseball betting odds action.

gets the ball in front of a hostile crowd for the San Francisco Giants on Thursday; he's 18-6 on the season. The Chicago Cubs, meanwhile, will counter with , who will be looking to improve on his 20-5 mark.

Odds Shark prediction models pick the Cubs to win this game 0.2-. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs Chicago Cubs Matchup

Team Betting Records & Power Rankings

Chicago (106-59) will face the 89-78 Giants in this tilt. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs San Francisco injuries news.

This game matches up the No. 1 (Chicago Cubs) and the No. 10 (San Francisco Giants) teams, according to our current MLB Power Rankings.

Statistical Matchup

Offensively, the game matches up Chicago Cubs No. 3 ranked offense (4.97 runs per game) against a San Francisco Giants defense and pitching staff that sits at No. 4 at 3.88 runs allowed per game. The Chicago Cubs have been averaging 8.64 hits per game, less than the San Francisco Giants have managed so far this season (8.84 hits on average).

Comparing defensive stats, San Francisco owns the No. 6-rated road mark, allowing 3.94 runs per game on the highway. Chicago, on the other hand, rates No. 7 in scoring at home.