MLB Odds Betting - San Francisco Giants Underdogs vs Astros at Houston

The Houston Astros get a visit from the San Francisco Giants in MLB baseball betting action on Wednesday, with the home side looking to send the visitors to the showers with a loss.

Houston hands the ball to starter Justin Verlander in this one and he'll try to improve on his 5-2 mark on the year. San Francisco counters with Jeff Samardzija, who will try to quiet the fans and the Astros bats at the same time.

Sportsbook Odds & Computer Pick

Sportsbooks such as Sportsbook had installed the Houston Astros as -240 moneyline favorites in this particular MLB betting odds matchup. The total, meanwhile, was set early at 7.5 before betting at Sportsbook started to move the line.

Prediction-scoring formulas run on this game pick a potential 5.4-1.6 result in favor of the Astros. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

San Francisco Giants vs Houston Astros Matchup

Team Betting Records & Power Rankings

The Houston Astros sport a record of 31-18 heading into this matchup, while the San Francisco Giants sit at 24-25 on the season Stay Informed: follow us on Twitter for odds specials, betting line moves and Houston vs San Francisco injuries news.

This game puts the Houston Astros, most recently No. 2 in Odds Shark MLB Power Rankings, up against the San Francisco Giants, who rate a No. 19 in the latest survey.

Statistical Matchup

At the plate, Houston owns the No. 12 ranking for hits at 8.61 per game. By contrast, the San Francisco Giants are rated No. 5 in the same category at 9 per game.

Houston owns the No. 1 defense, allowing 4.73 men per game to cross the plate. That contrasts with San Francisco's No. 23-rated defense.