St. Louis Cardinals Face the Chicago Cubs Wednesday: MLB Odds and Betting Trends

The MLB baseball betting odds board sees a clash between Chicago and St. Louis on Wednesday, with the host Cubs trying to win for themselves and reward betting fans who pick them on the moneyline.

Michael Wacha gets the ball in front of a hostile crowd for the St. Louis Cardinals on Wednesday; he's 10-3 on the season. The Chicago Cubs, meanwhile, will counter with Jason Hammel, who will be looking to improve on his 5-4 mark.

Sportsbook Odds & Computer Pick

Sportsbooks such as Sportsbook had installed the Chicago Cubs as 100 moneyline underdogs in this particular MLB betting odds matchup. The total, meanwhile, was set early at 7 before betting at Sportsbook started to move the line.

Handicapping models based on recent betting stats and prediction formulas pick a 4.2-4.1 win for the Cubs. A 4.2-4.1 result in favor of the Cubs is the prediction by the Odds Shark handicapping pick engine. View the computer score prediction and who will win the pick on the moneyline for all upcoming MLB matchups here.

St. Louis Cardinals vs Chicago Cubs Matchup

Team Betting Records & Power Rankings

The Chicago Cubs bring a 46-37 record to the battle against the 54-30 Cardinals. Stay Informed: follow us on Twitter for odds specials, betting line moves and Chicago vs St. Louis injuries news.

This game matches up the No. 8 (Chicago Cubs) and the No. 6 (St. Louis Cardinals) teams, according to our current MLB Power Rankings.

Statistical Matchup

Rating these teams in several key categories is important for handicappers and Chicago has baseball's No. 24-rated offensive output, at 8.17 hits per game. The St. Louis Cardinals average 8.75 hits per game, good for No. 10 on the list.

St. Louis brings the No. 1-rated defense to this matchup, facing the Cubs's No. 6-ranked defense.