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Max Muncy (left) and the Dodgers are favored in the Cardinals vs Dodgers odds

The Los Angeles Dodgers (104-46) are 6-1 in their last seven home games against the St. Louis Cardinals (88-63). The Dodgers will try to pick up another home win over St. Louis as a Cardinals vs Dodgers prediction in Friday’s opener of a three-game series in Los Angeles.

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Cardinals vs Dodgers Betting Preview

Cardinals vs Dodgers Opening Odds

The Dodgers opened as a -175 favorite at home before betting action on them bumped the Cardinals vs Dodgers odds up to -185. St. Louis is listed as a +153 underdog while the total has settled in at 8 runs after opening at 8.5 runs. The UNDER is 5-1 in St. Louis’ last six games.

Get the best Cardinals vs Dodgers odds and lines available from our recommended sportsbooks for your favorite picks of the night.

  • Best Spread
    -140
    +135
    STL+1.5
    -1.5LA
  • Best Moneyline
    +143
    -152
    STL
    LA
  • Best Total
    -105
    -108
    Over8
    8Under

Starting Pitchers

Jose Quintana has been fantastic for the St. Louis Cardinals with a 2.44 ERA and a 1.19 WHIP in nine starts since being acquired at the trade deadline from the Pittsburgh Pirates. Quintana enters Friday night’s game with a 5-6 record, a 3.16 ERA and a 1.25 WHIP on the season in 151 innings pitched.

Andrew Heaney pitched four shutout innings before being pulled from Los Angeles’ 4-3 win over the San Francisco Giants last Sunday due to a short rain delay. Heaney brings a 2.66 ERA and a 1.05 WHIP in 61 innings pitched this season into this start against the Cardinals.

St. Louis Finally Snapped Scoreless Streak On Thursday 

After suffering three straight shutout losses – against the Cincinnati Reds on Sunday and the San Diego Padres on Tuesday and Wednesday – the Cardinals finally produced some offense in a 5-4 win over San Diego on Thursday night. Brendan Donovan did most of the damage with a grand slam in the top of the seventh inning to give St. Louis a 5-3 lead.

Prior to those three straight scoreless losses, the Cardinals were 6-2 over their previous eight games. The offense will try to build on Thursday’s five-run effort against a Dodgers club that ranks best in the majors with a team ERA of 2.80. 

Los Angeles Looking To Finish Up This Homestand Strong

The Dodgers played five straight home games against the Arizona Diamondbacks this week and went 3-2, most recently beating Arizona 3-2 on Thursday to snap a two-game losing streak. Both of those losses came after the Dodgers closed as favorites of over -300.

Los Angeles was 9-1 in the 10 games that came before those surprising back-to-back losses. Max Muncy went 2-for-4 with two RBIs in Thursday’s win. Muncy is batting .317 in September, bringing his 2022 batting average up to .205 after starting the month with a .186 average.

Cardinals Player Prop: Paul Goldschmidt To Hit A Home Run (+300)

Paul Goldschmidt hasn’t hit a home run in his last 12 games, so some might argue he’s due given that he’s St. Louis’ leading home run hitter with 35 bombs this season. Andrew Heaney has allowed 11 big flies over his last five starts, so maybe it will be Goldschmidt who gets one here.

Dodgers Player Prop: Andrew Heaney OVER 6.5 Strikeouts (+102)

Andrew Heaney fanned eight batters in just four innings of work in his last start against the Giants. Heaney has struck out at least eight batters in five of his last six games, and he should be able to keep that trend rolling against this cold Cardinals offense.

Cardinals: Keys To Victory

St. Louis has scored only six total runs over its last five games. The Cardinals are unlikely to get their offense going against Andrew Heaney and the Dodgers’ dominant bullpen, so it will be up to Jose Quintana to keep pitching well to give St. Louis the edge as a Cardinals vs Dodgers prediction.

Dodgers: Keys To Victory

While the Dodgers haven’t been as cold on offense as St. Louis has, they have only scored two runs per game over their last three games. Getting things going again on offense will help make things easier for Heaney en route to a home win as a Cardinals vs Dodgers pick.

MLB Computer Pick: OVER 8 Runs

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Shark Bites
  • St. Louis is 4-10 in its last 14 games vs Los Angeles.
  • Los Angeles is 10-3 in its last 13 games.
  • The UNDER is 5-1 in Los Angeles’ last 6 games.