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The Boston Red Sox take on the Toronto Blue Jays on Tuesday night.

The Toronto Blue Jays (6-4) and Boston Red Sox (5-5) better get used to each other as they play seven times in the next 10 days beginning tonight. Last year’s season series was tight with Boston winning 10 of 19 meetings. For more insight, analysis and a Blue Jays vs Red Sox prediction, keep reading below. 

Blue Jays vs Red Sox Betting Preview

Blue Jays vs Red Sox Odds & Analysis

Opening Odds

Oddsmakers have the Red Sox as slight favorites for the series opener, despite the fact the Jays have won four of their last five games against Boston. The total opened at 9.5 but has fallen to 9 on most sites. If you like the OVER, you may want to check out PowerPlay.com, which has set the total at 6.5.

Get the best Blue Jays vs Red Sox odds and lines available from our recommended sportsbooks for your favorite picks of the night.

  • Best Spread
    -160
    +140
    TOR+1.5
    -1.5BOS
  • Best Moneyline
    +125
    -135
    TOR
    BOS
  • Best Total
    -105
    -105
    Over9.5
    9.5Under

Starting Pitchers

Yusei Kikuchi will make his second start as a Blue Jay. He lasted just 3.1 innings last week in a loss to the Yankees, although to be fair, he did not receive any run support in that game. Kikuchi is 0-2 in three career starts against the Red Sox.  

Boston will send veteran Nathan Eovaldi to the bump. He is 1-0 in two starts this season, but has been prone to the long ball, giving up four home runs in those two starts. He has just one win in eight career starts vs the Jays.

Blue Jays Set For A Long Stretch Of Baseball

Beginning tonight, Toronto will play 20 games in 20 days with no days off during that stretch. This will give the team a chance to get into a groove and find some consistency as they have alternated wins and losses in their last nine games. So if you believe in trends, then they are due for a loss as they are coming off a 4-3 win over Oakland on Sunday. 

Vladimir Guerrero Jr. is ripping the cover off the ball to begin the season. He has five home runs already, which is tied for the most in the majors. The Blue Jays have hit 14 as a team, which ranks third behind the Angels and Braves. 

Despite the ho-hum start, Toronto has the second-best odds to win the World Series at +800.

Red Sox Searching For Consistency

Boston is coming off a series split with the Minnesota Twins after losing the finale of the four-game set yesterday. In their two wins, the Red Sox allowed just one run, while they gave up a combined 16 in the two losses.  

Third baseman Rafael Devers, shortstop Xander Bogaerts and outfielder Alex Verdugo are leading the offensive charge for the Red Sox. All three players are hitting at least .333 and have combined for six home runs and 20 RBIs this season. 

Boston has won four of its last six games overall. 

Blue Jays vs Red Sox Pick & Insights

Blue Jays: Keys To Victory

George Springer is one of the best leadoff hitters in baseball but has struggled against Eovaldi throughout his career, going just 1-for-12 with four strikeouts. If he can get on base and set the tone, allowing the Jays’ big bats to do their thing, then taking the road dogs may be the wise choice when making your Blue Jays vs Red Sox pick.  

Red Sox: Keys To Victory

Get more from the entire lineup. Trevor Story has yet to make an impact with his new team, while J.D. Martinez, Jackie Bradley Jr. and Kike Hernandez are all struggling. If they get production from someone other than the aforementioned Devers, Bogaerts and Verdugo, a Boston bet could be the wise play.    

Odds Shark’s Computer Blue Jays vs Red Sox Prediction: Red Sox -135 ML

Check out more of Odds Shark’s signature MLB computer picks, plus our favorite sportsbooks that serve baseball customers. 

Shark Bites
  • The OVER is 7-2 in Boston’s last 9 home games.
  • The UNDER is 9-1 in Toronto’s last 10 road games.
  • The UNDER is 4-1 in the last 5 meetings in Boston.

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