Detroit hasn't won since 1984, while the Giants are looking for their second World Series title in three seasons.
The World Series odds, however, favor the Tigers as they opened as -175 series favorites at online sportsbooks such as Sportsbook.
The Giants, who rallied from 3-1 down to beat St. Louis, are +155 underdogs.
Triple Crown Sportsbook Miguel Cabrera is the early World Series MVP odds favorite, followed closely by Giants catcher Buster Posey. Cabrera was 5/1 at Sportsbook while Posey was 13/2.
As with all major sporting events, prop odds add plenty of spice and wagering product to the action.
You can wager on the exact series result (4-1 Detroit is the favorite position) and over-under on the number of games.
Check out all the latest World Series props and Game 1 betting lines at Sportsbook:
Series Price
Detroit Tigers (Series Prices) -175
San Francisco Giants (Series Prices) +155
Game 1 Lines Runline Moneyline Totals
Detroit Tigers -1.5 (-105) -170 O 7.0 (+110)
San Francisco Giants 1.5 (-115) +155 U 7.0 (-130)
World Series MVP Odds
Miguel Cabrera (DET) 5/1
Buster Posey (SF) 13/2
Justin Verlander (DET) 8/1
Prince Fielder (DET) 8/1
Delmon Young (DET) 12/1
Hunter Pence (SF) 12/1
Marco Scutaro (SF) 12/1
Pablo Sandoval (SF) 12/1
Angel Pagan (SF) 14/1
Austin Jackson (DET) 14/1
Alex Avila (DET) 20/1
Avisail Garcia (DET) 20/1
Brandon Belt (SF) 20/1
Brandon Crawford (SF) 20/1
Jhonny Peralta (DET) 20/1
Omar Infante (DET) 20/1
Andy Dirks (DET) 25/1
Gregor Blanco (SF) 25/1
Any Other Player 12/1
Additional Game 1 Props
Total Strikeouts – Justin Verlander 7.5
Total Strikeouts – Barry Zito 3.5
Totals Hits Runs and RBI’s
Miguel Cabrera (DET) -190
Buster Posey (SF) +155
Prince Fielder (DET) -150
Pablo Sandoval (SF) +120
Delmon Young (DET) +105
Hunter Pence (SF) -135
Austin Jackson (DET) -175
Marco Scutaro (SF) +145
Additional Series Props - Series Spread
San Francisco Giants +1½ (-130)
Detroit Tigers -1½ (EVEN)
San Francisco Giants +2½ (-290)
Detroit Tigers -2½ (+230)
San FranciscoGiants -1½ (+300)
DetroitTigers +1½ (-400)
Exact Result
San Francisco Giants 4-0 +1800
San Francisco Giants 4-1 +900
San Francisco Giants 4-2 +550
San Francisco Giants 4-3 +450
Detroit Tigers 4-0 +750
Detroit Tigers 4-1 +350
Detroit Tigers 4-2 +400
Detroit Tigers 4-3 +450
Number of Games
Over 5½ (-165)
Under 5½ (+135)
Number of Games
Over 4½ (-1000)
Under 4½ (+600)
Number of Games
4 +600
5 +240
6 +200
7 +200
